{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T03:15:28Z","timestamp":1762917328455},"reference-count":16,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2011,10,25]],"date-time":"2011-10-25T00:00:00Z","timestamp":1319500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp; Gyne"],"published-print":{"date-parts":[[2011,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To investigate changes in abdominal circumference (AC) and umbilical artery pulsatility index (UA\u2010PI) with gestation in fetuses with isolated gastroschisis, and to determine whether a relationship exists between UA\u2010PI and fetal AC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data from 58 pregnancies with isolated gastroschisis diagnosed at between 24 and 36 weeks' gestation were included in the study. <jats:italic>Z<\/jats:italic>\u2010scores were calculated with respect to expected UA\u2010PI values in normal pregnancies after log\u2010transformation. AC\u2010<jats:italic>Z<\/jats:italic>\u2010scores were calculated with respect to expected size in normal pregnancies according to a standard chart. Functional linear discriminant analysis (FLDA) was applied to generate 50<jats:sup><jats:italic>th<\/jats:italic><\/jats:sup>, 5<jats:sup><jats:italic>th<\/jats:italic><\/jats:sup> and 95<jats:sup><jats:italic>th<\/jats:italic><\/jats:sup> percentile curves for changes in both AC and UA\u2010PI with gestational age in fetuses with gastroschisis. These curves were compared with the standard curves, as were the means. UA\u2010PI was also plotted against AC. For this relationship, a robust Spearman correlation coefficient was obtained with FLDA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In fetuses with gastroschisis, there was a highly significant negative correlation between UA\u2010PI and AC, normalized for gestation using <jats:italic>Z<\/jats:italic>\u2010scores (median correlation coefficient, \u2212 0.289; median <jats:italic>P<\/jats:italic> = 0.000023). Moreover, compared with standard curves AC was lower and UA\u2010PI higher in the gestational\u2010age range studied. Both the AC and UA\u2010PI curves showed a significantly different rate of change with gestation compared with the normal ranges. The mean values for fetuses with gastroschisis compared with the standard AC and UA\u2010PI range curves were significantly different for AC throughout gestation, and for UA\u2010PI from 32 weeks' gestation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In fetal gastroschisis, it is well known that AC tends to be smaller, though UA\u2010PI has not been reported to be abnormal in any consistent way. There is a clear relationship between the fetus's AC for gestation and UA\u2010PI, which is not the case for normally grown fetuses. The data suggest that the growth restriction seen in gastroschisis may be explained by hypoxia, and not simply by the classical explanation of extra\u2010abdominal displacement of the abdominal viscera. Copyright \u00a9 2011 ISUOG. Published by John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/uog.8947","type":"journal-article","created":{"date-parts":[[2011,1,24]],"date-time":"2011-01-24T12:45:52Z","timestamp":1295873152000},"page":"538-542","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Umbilical artery pulsatility index and fetal abdominal circumference in isolated gastroschisis"],"prefix":"10.1002","volume":"38","author":[{"given":"U.","family":"Hussain","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Daemen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Missfelder\u2010Lobos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"De Moor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Timmerman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Bourne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Lees","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,10,25]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.85"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2008.03.024"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1159\/000103295"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/1467-9868.00297"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/den382"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-9473(98)00040-1"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1868"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1994.tb13077.x"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1997.10050356.x"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/pd.386"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-007-1960-4"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9926(199606)54:2<84::AID-TERA4>3.0.CO;2-4"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20446"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.32897"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3016.2008.00990.x"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2007.10.008"}],"container-title":["Ultrasound in Obstetrics &amp; Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fuog.8947","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/uog.8947","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,8]],"date-time":"2023-10-08T18:20:24Z","timestamp":1696789224000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/uog.8947"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,10,25]]},"references-count":16,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2011,11]]}},"alternative-id":["10.1002\/uog.8947"],"URL":"https:\/\/doi.org\/10.1002\/uog.8947","archive":["Portico"],"relation":{},"ISSN":["0960-7692","1469-0705"],"issn-type":[{"value":"0960-7692","type":"print"},{"value":"1469-0705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,10,25]]},"assertion":[{"value":"2011-01-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-10-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}