{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T10:11:32Z","timestamp":1776852692323,"version":"3.51.2"},"reference-count":15,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ultrasound in Obstet &amp;amp; Gyne"],"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report on the pre\u2010 and postnatal cytogenetic, molecular genetic and clinical findings in monochorionic\u2010diamniotic twins discordant for trisomy 18. Structural anomalies were identified in one of the twins on prenatal ultrasound examination at 20 weeks' gestation and sampling of amniotic fluid from both sacs was performed for karyotyping. This revealed trisomy 18 in the twin with abnormalities and a normal karyotype in the other twin. Elective Cesarean section was performed at 31 + 5 weeks and the aneuploid twin died shortly after delivery. The surviving twin showed low\u2010grade mosaicism for trisomy 18 on postnatal analysis but has shown normal development. For prenatal diagnosis in monochorionic\u2010diamniotic twin pregnancy the sampling of both amniotic sacs is recommended, especially if one twin has structural anomalies on ultrasound scan. Copyright \u00a9 2011 ISUOG. Published by John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/uog.8978","type":"journal-article","created":{"date-parts":[[2011,3,2]],"date-time":"2011-03-02T18:48:56Z","timestamp":1299091736000},"page":"727-728","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Monozygotic twins discordant for trisomy 18"],"prefix":"10.1002","volume":"38","author":[{"given":"A.","family":"Reuss","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Gerlach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Bedow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Landt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U.","family":"Kuhn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Stein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Reschke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Albrecht","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Westrich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Trawicki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Eiben","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,11]]},"reference":[{"key":"e_1_2_3_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19960122)61:3<216::AID-AJMG5>3.0.CO;2-S"},{"key":"e_1_2_3_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320110204"},{"key":"e_1_2_3_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.32431"},{"key":"e_1_2_3_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0223(199901)19:1<72::AID-PD465>3.0.CO;2-V"},{"key":"e_1_2_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2008.01.095"},{"key":"e_1_2_3_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/pd.383"},{"key":"e_1_2_3_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19980106)75:1<40::AID-AJMG9>3.0.CO;2-U"},{"key":"e_1_2_3_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.22.1.6"},{"key":"e_1_2_3_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970100105"},{"key":"e_1_2_3_11_2","first-page":"551","article-title":"Sexual discordance in monozygotic twins","volume":"37","author":"Perlman EJ","year":"1990","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_3_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0223(200012)20:12<999::AID-PD948>3.0.CO;2-E"},{"key":"e_1_2_3_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1746"},{"key":"e_1_2_3_14_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0001566000002154"},{"key":"e_1_2_3_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447-0756.2009.01115.x"},{"key":"e_1_2_3_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/pd.2031"}],"container-title":["Ultrasound in Obstetrics &amp; Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fuog.8978","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/uog.8978","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T07:31:20Z","timestamp":1697441480000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/uog.8978"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["10.1002\/uog.8978"],"URL":"https:\/\/doi.org\/10.1002\/uog.8978","archive":["Portico"],"relation":{},"ISSN":["0960-7692","1469-0705"],"issn-type":[{"value":"0960-7692","type":"print"},{"value":"1469-0705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,11]]},"assertion":[{"value":"2011-02-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-11-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}