{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T12:00:23Z","timestamp":1761566423778,"version":"build-2065373602"},"reference-count":10,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T00:00:00Z","timestamp":1637539200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[2022,4]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Spontaneous week\u2010to\u2010week variation in the presence and intensity of innocent cardiac murmurs in individual puppies is unknown.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Sixty privately owned, clinically healthy Cairn terrier and Dachshund puppies between 4 and 8\u00a0weeks of age were included. All dogs underwent weekly cardiac auscultation at the breeders\u2019 home by a veterinary cardiology specialist using an acoustic stethoscope. On each occasion, a phonocardiogram was recorded with an electronic stethoscope. Furthermore, all dogs were auscultated once at a first opinion veterinary practise and once at the authors\u2019 institution, where they also underwent an echocardiographic examination.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Two\u2010hundred and eighty\u2010one auscultations were conducted on 32 Cairn terriers and 28 Dachshunds, at the breeders\u2019 homes. Innocent murmurs were detected in 19 puppies. Two of these puppies had a detectable murmur on each auscultation. In five of the puppies, the murmur became undetectable during the observation period and in 12 puppies the murmur was intermittently audible. Auscultation at the authors\u2019 institution had an unpredictable effect on murmur presence and intensity. Phonocardiography revealed murmurs in 42 puppies. Interpretation of phonocardiograms by two independent observers showed nearly perfect agreement (\u03ba\u00a0=\u00a00.859).<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Remarkable and unpredictable spontaneous week\u2010to\u2010week variation was documented in the presence and intensity of innocent murmurs.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/vetr.1173","type":"journal-article","created":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T12:58:24Z","timestamp":1637585904000},"source":"Crossref","is-referenced-by-count":1,"title":["Temporal changes in the presence and intensity of innocent cardiac murmurs in clinically healthy Cairn terrier and Dachshund puppies between 4 and 8\u00a0weeks of age"],"prefix":"10.1002","volume":"190","author":[{"given":"Donny","family":"Rigterink","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariska A.","family":"L'Herminez","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0273-6586","authenticated-orcid":false,"given":"Viktor","family":"Szatm\u00e1ri","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Faculty of Veterinary Medicine Utrecht University Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,11,22]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.13632"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvc.2015.05.001"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.14667"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2019.04.002"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13028-020-00535-1"},{"volume-title":"Cardiac auscultation and phonocardiography in dogs, horses and cats","year":"2002","author":"Kvart C","key":"e_1_2_11_7_1"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.1993.tb01015.x"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(95)00571-4"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2004.tb00221.x"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1623629"}],"container-title":["Veterinary Record"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/vetr.1173","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/vetr.1173","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bvajournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/vetr.1173","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:47:08Z","timestamp":1761562028000},"score":1,"resource":{"primary":{"URL":"https:\/\/bvajournals.onlinelibrary.wiley.com\/doi\/10.1002\/vetr.1173"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,22]]},"references-count":10,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["10.1002\/vetr.1173"],"URL":"https:\/\/doi.org\/10.1002\/vetr.1173","archive":["Portico"],"relation":{},"ISSN":["0042-4900","2042-7670"],"issn-type":[{"type":"print","value":"0042-4900"},{"type":"electronic","value":"2042-7670"}],"subject":[],"published":{"date-parts":[[2021,11,22]]},"article-number":"e1173"}}