{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T20:45:34Z","timestamp":1779914734596,"version":"3.53.1"},"reference-count":22,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T00:00:00Z","timestamp":1648512000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[2022,5]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n To the authors\u2019 knowledge, the effect of a combination of butorphanol tartrate and detomidine hydrochloride on the laryngeal function and symmetry of the arytenoid cartilages in young Thoroughbred horses has not been examined. Therefore, this study aimed to examine the effects of administration of butorphanol and detomidine on left\u2010to\u2010right rima glottidis ratio (L:R RGR), cross\u2010sectional area of the rima glottidis (CSARG) and grade of laryngeal function of Thoroughbred yearlings examined endoscopically at rest.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Forty\u2010six Thoroughbred yearlings underwent laryngeal video endoscopy, at rest, before and after sedation with butorphanol and detomidine. Three clinicians assigned grades of laryngeal function after reviewing the video recordings. The L:R RGR and CSARG were measured at the point of arytenoid cartilages\u2019 maximal abduction. Student's\n t<\/jats:italic>\n \u2010test was used to compare the L:R RGR and CSARG. Cohen's kappa (\n \u03ba<\/jats:italic>\n ) was used to compare the intra\u2010 and interobserver agreements. Spearman's rank order was used to assess agreement between CSARG and grade of laryngeal function.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Sedation had no effect on L:R RGR and CSARG. Mean intraobserver agreement of grade of laryngeal function of unsedated yearlings was 93.1%, and that of sedated yearlings was 92.9%. Mean interobserver agreement of grade of laryngeal function of unsedated yearlings was 92.8%, and that of sedated yearlings was 92.7%. Correlation between CSARG and laryngeal function grade was significant for both groups (\n p<\/jats:italic>\n \u00a0<\u00a00.001).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Sedating Thoroughbred yearlings with detomidine and butorphanol, before endoscopically examining the larynx, did not significantly affect the grade of laryngeal function.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/vetr.1483","type":"journal-article","created":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T00:09:21Z","timestamp":1648598961000},"source":"Crossref","is-referenced-by-count":2,"title":["Effect of a combination of butorphanol and detomidine on endoscopic assessment of laryngeal function in Thoroughbred yearlings"],"prefix":"10.1002","volume":"190","author":[{"given":"Hugo","family":"Almonte","sequence":"first","affiliation":[{"name":"Park Equine Hospital Lexington Kentucky USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Schumacher","sequence":"additional","affiliation":[{"name":"Department of Large Animal Clinical Sciences College of Veterinary Medicine University of Tennessee Knoxville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher R.","family":"Johnson","sequence":"additional","affiliation":[{"name":"Park Equine Hospital Lexington Kentucky USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey T.","family":"Berk","sequence":"additional","affiliation":[{"name":"Equine Medical Associates Lexington Kentucky USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rhodes P.","family":"Bell","sequence":"additional","affiliation":[{"name":"Park Equine Hospital Lexington Kentucky USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,3,29]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2001.219.962"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.236.6.669"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516402776181169"},{"key":"e_1_2_10_5_1","volume-title":"Equine surgery","author":"Stick JA","year":"2018"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0737-0806(85)80112-X"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1987.tb02666.x"},{"key":"e_1_2_10_8_1","first-page":"34","article-title":"Evaluation of the young horse upper airway: what is normal, and what is acceptable?","volume":"44","author":"Embertson RM","year":"1998","journal-title":"Proc Am Ass Equine Practnrs"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/evj.12061"},{"key":"e_1_2_10_10_1","first-page":"93","article-title":"Havemeyer Foundation Monograph Series No. 11. 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Stratford\u2010upon\u2010Avon, Warwickshire, England","author":"Dixon PM","year":"2004","journal-title":"Havemeyer Foundation"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516406778400619"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1991.tb02731.x"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516407X204177"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/vsu.13334"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaa.2019.06.002"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.1991.tb00331.x"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/evj.12331"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-950X.1991.tb00332.x"},{"key":"e_1_2_10_19_1","first-page":"1","article-title":"Guidelines of the minimum sample size requirements for Cohen's Kappa","volume":"14","author":"Mohamad AB","year":"2017","journal-title":"Epidemiol Biostat Public Health"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaa.2018.02.011"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199804000-00010"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516409X423073"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/evj.13030"}],"container-title":["Veterinary Record"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/vetr.1483","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/vetr.1483","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bvajournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/vetr.1483","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T12:10:28Z","timestamp":1761653428000},"score":1,"resource":{"primary":{"URL":"https:\/\/bvajournals.onlinelibrary.wiley.com\/doi\/10.1002\/vetr.1483"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,29]]},"references-count":22,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10.1002\/vetr.1483"],"URL":"https:\/\/doi.org\/10.1002\/vetr.1483","archive":["Portico"],"relation":{},"ISSN":["0042-4900","2042-7670"],"issn-type":[{"value":"0042-4900","type":"print"},{"value":"2042-7670","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,29]]},"article-number":"e1483"}}