{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T17:11:57Z","timestamp":1787505117881,"version":"build-2736575974"},"reference-count":52,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,4,29]],"date-time":"2022-04-29T00:00:00Z","timestamp":1651190400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Interest in meibomian gland dysfunction (MGD) is growing in veterinary medicine. However, research on MGD in dogs is lacking. The aims of this study were to compare the interferometry grades, tear meniscus height (TMH) and non\u2010invasive tear break\u2010up time (NIBUT) grades between dogs with and without MGD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Routine ophthalmic examination, interferometry, NIBUT assessment, TMH measurement and meibography were performed. Age and Schirmer tear test\u20101 (STT\u20101) results were compared between the control and MGD groups using Student's\n                      <jats:italic>t<\/jats:italic>\n                      \u2010test. Interferometry grades, NIBUT grades and TMH were compared between the two groups using Mann\u2013Whitney\n                      <jats:italic>U<\/jats:italic>\n                      \u2010test.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There was no significant difference in age between the two groups (\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      =\u00a00.279). STT\u20101 (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.024), interferometry (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.004) and NIBUT grades (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.012) were significantly lower in the MGD group than in the control group. No significant difference in TMH values (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.587) was observed between the two groups. While the control group included 18 and seven eyes in meiboscore 0 and 1, in MGD group, 12, eight, five and three eyes were included in meiboscore 0, 1, 2 and 3, respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Low interferometry and NIBUT grades were associated with MGD, suggesting decreased meibum and disrupted tear film quality. TMH did not differ between the two groups. Meibography could aid in the diagnosis of MGD in severe cases, although it could not detect early MGD in the dogs in this study.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/vetr.1682","type":"journal-article","created":{"date-parts":[[2022,4,29]],"date-time":"2022-04-29T13:55:45Z","timestamp":1651240545000},"source":"Crossref","is-referenced-by-count":17,"title":["Evaluation of ocular surface parameters in dogs with and without meibomian gland dysfunction"],"prefix":"10.1002","volume":"191","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6129-2391","authenticated-orcid":false,"given":"Dajeong","family":"Jeong","sequence":"first","affiliation":[{"name":"Department of Veterinary Clinical Sciences College of Veterinary Medicine and Research Institute for Veterinary Science Seoul National University  Seoul 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