{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T23:19:55Z","timestamp":1776122395071,"version":"3.50.1"},"reference-count":37,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,4,22]],"date-time":"2021-04-22T00:00:00Z","timestamp":1619049600000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Objectives<\/jats:bold>\n                    : The aim of the study was to find evidence of SARS\u2010CoV\u20102 infection in UK cats.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Design<\/jats:bold>\n                    : Tissue samples were tested for SARS\u2010CoV\u20102 antigen using immunofluorescence and for viral RNA by in situ hybridisation. A set of 387 oropharyngeal swabs that had been submitted for routine respiratory pathogen testing was tested for SARS\u2010CoV\u20102 RNA using reverse transcriptase quantitative PCR.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results<\/jats:bold>\n                    : Lung tissue collected\n                    <jats:italic>post\u2010mortem<\/jats:italic>\n                    from cat 1 tested positive for both SARS\u2010CoV\u20102 nucleocapsid antigen and RNA. SARS\u2010CoV\u20102 RNA was detected in an oropharyngeal swab collected from cat 2 that presented with rhinitis and conjunctivitis. High throughput sequencing of the viral genome revealed five single nucleotide polymorphisms (SNPs) compared to the nearest UK human SARS\u2010CoV\u20102 sequence, and this human virus contained eight SNPs compared to the original Wuhan\u2010Hu\u20101 reference sequence. An analysis of the viral genome of cat 2 together with nine other feline\u2010derived SARS\u2010CoV\u20102 sequences from around the world revealed no shared cat\u2010specific mutations.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions<\/jats:bold>\n                    : These findings indicate that human\u2010to\u2010cat transmission of SARS\u2010CoV\u20102 occurred during the COVID\u201019 pandemic in the UK, with the infected cats developing mild or severe respiratory disease. Given the ability of the new coronavirus to infect different species, it will be important to monitor for human\u2010to\u2010cat, cat\u2010to\u2010cat and cat\u2010to\u2010human transmission.\n                  <\/jats:p>","DOI":"10.1002\/vetr.247","type":"journal-article","created":{"date-parts":[[2021,4,23]],"date-time":"2021-04-23T02:00:29Z","timestamp":1619143229000},"source":"Crossref","is-referenced-by-count":69,"title":["Detection of SARS\u2010CoV\u20102 in respiratory samples from cats in the UK associated with human\u2010to\u2010cat transmission"],"prefix":"10.1002","volume":"188","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4313-5023","authenticated-orcid":false,"given":"Margaret J.","family":"Hosie","sequence":"first","affiliation":[{"name":"MRC\u2010University of Glasgow Centre for Virus Research  Glasgow UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilaria","family":"Epifano","sequence":"additional","affiliation":[{"name":"MRC\u2010University of 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