{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T07:04:28Z","timestamp":1761635068033,"version":"build-2065373602"},"reference-count":14,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2021,4,19]],"date-time":"2021-04-19T00:00:00Z","timestamp":1618790400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The Dogo Argentino dog breed is affected by hereditary congenital sensorineural deafness (CSD) associated with white pigmentation, but prevalence data and associations with phenotypes have not been reported.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In a retrospective study, animals were tested by the brainstem auditory evoked response, and phenotype data of sex, iris color, patch presence\/absence and parent hearing status were collected. Chi\u2010square analyses were performed to identify associations between deafness and phenotype traits.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      BAER results and phenotype data were collected for 811 dogs. Hearing status was 74.23% bilaterally hearing, 20.35% unilaterally deaf and 5.43% bilaterally deaf or an overall prevalence of 25.77%. CSD was not associated with sex, but dogs without a patch had a significantly higher prevalence rate than patched dogs. Blue\u2010eyed dogs had higher prevalence rates than brown\u2010eyed dogs, but because of small sample size the \u03c7\n                      <jats:sup>2<\/jats:sup>\n                      association was not considered valid. Insufficient numbers of dogs with a unilaterally deaf parent were present to assess the effects of parent hearing status.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Approximately one fourth of a US Dogo Argentino population was deaf in one or both ears, but dogs with a patch had a lower prevalence. Dogs with a blue eye were more likely to be deaf, but the association significance could not be reliably assessed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/vetr.299","type":"journal-article","created":{"date-parts":[[2021,4,19]],"date-time":"2021-04-19T03:39:40Z","timestamp":1618803580000},"source":"Crossref","is-referenced-by-count":1,"title":["Congenital sensorineural deafness in Dogo Argentino dogs: Prevalence and phenotype associations"],"prefix":"10.1002","volume":"188","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6084-4438","authenticated-orcid":false,"given":"George M.","family":"Strain","sequence":"first","affiliation":[{"name":"Comparative Biomedical Sciences School of Veterinary Medicine, Louisiana State University  Baton Rouge Louisiana USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,4,19]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2015.00029"},{"key":"e_1_2_9_3_1","unstructured":"StrainGM. Deafness in dogs and cats.2020.http:\/\/www.lsu.edu\/deafness\/deaf.htm. Accessed 20 November 2020."},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1090-0233(03)00104-7"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1746-6148-8-202"},{"key":"e_1_2_9_6_1","unstructured":"Dogo Argentino Club of America. Breed standard of the Dogo Argentino.2020.https:\/\/dogousa.org\/breedstandard. Accessed 20 November 2020."},{"key":"e_1_2_9_7_1","unstructured":"The Spruce Pets. Dogo Argentino: dog breed profile.2020.https:\/\/www.thesprucepets.com\/dogo\u2010argentino\u20104584341. 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