{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T16:28:57Z","timestamp":1794328137671,"version":"4.9.0"},"reference-count":21,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T00:00:00Z","timestamp":1684972800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T00:00:00Z","timestamp":1684972800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[2023,9,9]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n The objective of this study was to determine the threshold of the Bristol Rabbit Pain Scale (BRPS) indicating the need for intervention analgesia.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Fourteen members of veterinary staff were recruited to rate rabbits (\n n<\/jats:italic>\n = 71) in acute pain. Observers in group A (\n n<\/jats:italic>\n = 7) were asked to score each rabbit using the BRPS, while observers in group B (\n n<\/jats:italic>\n = 7) independently answered the question \u2018In your clinical capacity, do you think this animal requires analgesia?\u2019 with either 'Yes' or 'No'. The answers from the two groups were then compared.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Rabbits for which group B answered \u2018No\u2019 (\n n<\/jats:italic>\n = 36) had a median BRPS score (range) of 4 (0\u201310), while those for which group B answered \u2018Yes\u2019 (\n n<\/jats:italic>\n = 42) had a median BRPS score of 9 (1\u201318;\n Z<\/jats:italic>\n = \u20137.48;\n p<\/jats:italic>\n < 0.001). The area under the receiver operating characteristic curve was 0.85 (95% confidence interval: 0.77\u20130.93;\n p<\/jats:italic>\n \u2009<\u20090.001), indicating excellent discrimination of the BRPS with a cut\u2010off score of 5.5 (sensitivity 88.1% and specificity 69.4%). However, for practicality, a score of 5 was deemed a feasible cut\u2010off.\n <\/jats:p>\n <\/jats:sec>\n \n Limitations<\/jats:title>\n The main limitations of this study are the small rabbit sample size and the subjective nature of pain scoring in animals.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Analgesic intervention should be considered in rabbits with a pain score equal to or greater than 5 on the BRPS.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/vetr.2995","type":"journal-article","created":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T09:48:25Z","timestamp":1685008105000},"source":"Crossref","is-referenced-by-count":3,"title":["Determining a cut\u2010off point for intervention analgesia in rabbits using the Bristol Rabbit Pain Scale"],"prefix":"10.1002","volume":"193","author":[{"given":"Livia","family":"Benato","sequence":"first","affiliation":[{"name":"Animal Welfare and Behaviour School of Veterinary Sciences University of Bristol Langford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0456-5159","authenticated-orcid":false,"given":"Joanna","family":"Murrell","sequence":"additional","affiliation":[{"name":"Highcroft Veterinary Referrals Whitchurch UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Rooney","sequence":"additional","affiliation":[{"name":"Animal Welfare and Behaviour School of Veterinary Sciences University of Bristol Langford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,5,25]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000001939"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/08998280.2000.11927681"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaa.2018.10.007"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvex.2010.09.003"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaa.2021.09.020"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jepm.2011.11.010"},{"key":"e_1_2_11_8_1","unstructured":"2020_AAHA_Guidelines.2020. 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