{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:36:33Z","timestamp":1787243793465,"version":"build-2736575974"},"reference-count":49,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,8,25]],"date-time":"2024-08-25T00:00:00Z","timestamp":1724544000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[2024,10,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Treatment of\n                      <jats:italic>Vitis vinifera<\/jats:italic>\n                      fruit (VVF) ingestion can be challenging due to no clear toxic dose, signalment factors and variable clinical signs. Current treatment guidance is generalised: decontamination, aggressive fluid therapy, monitoring and\/or treatment of renal dysfunction. The objective of this study was to conduct a scoping review of scientific evidence regarding the ingestion of VVF in dogs. Three primary areas were reviewed: VVF types ingested, clinical signs reported and treatments given. The inclusion criterion was any paper presenting data on clinical signs or treatments of dogs that had ingested VVF (unprocessed VVF only).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The following databases were searched: CAB Abstracts, Medline, Embase and Scopus. No limits were placed on language or date. The review followed the Joanna Briggs Institute scoping review methodology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty\u2010four papers were identified. A wide range of VVF types were ingested, but the toxic dose was difficult to ascertain. The most commonly reported signs were gastrointestinal, renal, neurological and haematological. Treatment commonly consisted of fluid therapy, diuretics and antiemetics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Limitations<\/jats:title>\n                    <jats:p>This scoping review neither explored cases of processed VVF ingestion nor did it chart laboratory findings; therefore, potentially clinically significant findings in these areas may have been missed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>VVF ingestion typically causes gastrointestinal\/renal dysfunction, with no clear toxicity attributable to VVF type. Treatments varied according to the presence\/absence of clinical signs, and the prognosis was varied. Further research on current treatment efficacy is warranted, permitting an evidence\u2010based, risk\u2013benefit approach to be adopted by clinicians.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/vetr.4536","type":"journal-article","created":{"date-parts":[[2024,8,26]],"date-time":"2024-08-26T02:08:20Z","timestamp":1724638100000},"source":"Crossref","is-referenced-by-count":3,"title":["Scoping review exploring the evidence base on\n                    <i>Vitis vinifera<\/i>\n                    toxicity in dogs after ingestion: Clinical effects, treatments and types of\n                    <i>V. vinifera<\/i>"],"prefix":"10.1002","volume":"195","author":[{"given":"Joshua","family":"Downs","sequence":"first","affiliation":[{"name":"Centre for Evidence\u2010Based Veterinary Medicine University of Nottingham  Loughborough UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnieszka","family":"Zoltowska","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine and Science University of Nottingham  Loughborough UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Hackney","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine and Science University of Nottingham  Loughborough UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David S.","family":"Gardner","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine and Science University of Nottingham  Loughborough UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison","family":"Ashmore","sequence":"additional","affiliation":[{"name":"University of Nottingham Libraries University of Nottingham  Nottingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4893-6583","authenticated-orcid":false,"given":"Marnie L.","family":"Brennan","sequence":"additional","affiliation":[{"name":"Centre for Evidence\u2010Based Veterinary Medicine University of Nottingham  Loughborough UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,8,25]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.10-0177"},{"issue":"10","key":"e_1_2_11_3_1","article-title":"Raisin poisoning in a dog","volume":"152","author":"Penny D","year":"2003","journal-title":"Vet Rec"},{"issue":"1","key":"e_1_2_11_4_1","first-page":"63","article-title":"Hemodialysis in a dog with acute renal failure from currant toxicity","volume":"49","author":"Stanley SW","year":"2008","journal-title":"Can Vet J"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.15884"},{"issue":"10","key":"e_1_2_11_6_1","first-page":"1555","article-title":"Renal failure associated with ingestion of grapes or raisins in dogs","volume":"218","author":"Gwaltney\u2010Brant S","year":"2001","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/vec.13234"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2005.tb02744.x"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/vec.13025"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1534-6935.2004.00114.x"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/104063870501700302"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/vec.13294"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.12968\/vetn.2019.10.8.418"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1992.03490170092032"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.2003.tb11551.x"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsap.13483"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.46658\/JBIMES-20-12"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13643-016-0384-4"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/acref\/9780199976720.001.0001"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.14741"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncpneph0563"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.101745"},{"key":"e_1_2_11_23_1","unstructured":"RobinsonNJ.Use of sentinel practices to obtain data regarding common clinical conditions and presentations in small animal consultations. 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