{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T08:51:42Z","timestamp":1782463902405,"version":"3.54.5"},"reference-count":18,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,1,19]],"date-time":"2021-01-19T00:00:00Z","timestamp":1611014400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[2021,3]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:bold>\n : The aim of this study was to evaluate the histological tolerance of medical cyanoacrylate adhesives (CAs), butyl\u2010CA and octyl\u2010CA, applied by two different methods in surgical skin incisions of\n T. scripta<\/jats:italic>\n .\n <\/jats:p>\n \n Methods<\/jats:bold>\n : A two\u2010trial controlled blind study each one including 12 female adult\n T. scripta<\/jats:italic>\n turtles. Two 1\u2010cm long full\u2010thickness surgical skin incisions were made on the dorsal aspect of each hind limb. In trial 1 CAs were applied superficially over the apposed wound edges; each animal's four wounds were closed using butyl\u2010CA, octyl\u2010CA and ethyl\u2010CA or absorbable suture as controls. In trial 2 adhesives were applied holding wound edges everted, and octyl\u2010CA was replaced by a non\u2010sutured control wound. At each time point (2, 7, 14 and 21 days) all wounds from three randomly chosen animals were biopsied.\n <\/jats:p>\n \n Results<\/jats:bold>\n : Medical grade CAs did not induce any sign of tissue damage and\/or inflammatory reaction attributable to histotoxicity independently of the method of application. Wound dehiscence rate was higher when CAs were applied superficially over the apposed wound edges.\n <\/jats:p>\n \n Conclusions<\/jats:bold>\n : Octyl and butyl\u2010CA are well tolerated by turtles' soft skin but because of their high rate of dehiscence they are not recommended in high tension wounds; use in low tension wounds needs further investigation.\n <\/jats:p>","DOI":"10.1002\/vetr.59","type":"journal-article","created":{"date-parts":[[2021,1,19]],"date-time":"2021-01-19T13:35:32Z","timestamp":1611063332000},"source":"Crossref","is-referenced-by-count":2,"title":["Tissue tolerance to cyanoacrylate adhesives for closure of surgical wounds in\n Trachemys scripta<\/i>\n skin"],"prefix":"10.1002","volume":"188","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7542-169X","authenticated-orcid":false,"given":"Sayda","family":"P\u00e9rez\u2010Delgado","sequence":"first","affiliation":[{"name":"Department of Animal Medicine and Surgery, Facultad de Medicina Veterinaria Universidad de C\u00f3rdoba C\u00f3rdoba Spain"},{"name":"Department of Veterinary Medicine and Zootechnics, Escuela de Ciencias Agrarias y Veterinarias Universidad Nacional Aut\u00f3noma de Nicaragua Le\u00f3n Nicaragua"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Mozos","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Comparative Pathology, Facultad de Medicina Veterinaria Universidad de C\u00f3rdoba C\u00f3rdoba Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"Guerra","sequence":"additional","affiliation":[{"name":"Veterinary Service Department Zoological Garden of C\u00f3rdoba C\u00f3rdoba Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosario","family":"Lucena","sequence":"additional","affiliation":[{"name":"Department of Animal Medicine and Surgery, Facultad de Medicina Veterinaria Universidad de C\u00f3rdoba C\u00f3rdoba Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ver\u00f3nica","family":"Molina","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Comparative Pathology, Facultad de Medicina Veterinaria Universidad de C\u00f3rdoba C\u00f3rdoba Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro J.","family":"Ginel","sequence":"additional","affiliation":[{"name":"Department of Animal Medicine and Surgery, Facultad de Medicina Veterinaria Universidad de C\u00f3rdoba C\u00f3rdoba Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,1,19]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvex.2015.08.011"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-196507000-00017"},{"issue":"2","key":"e_1_2_9_4_1","first-page":"199","article-title":"Comparison of 2\u2010ethyl\u2010cyanoacrylate and 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