{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T13:10:48Z","timestamp":1778332248573,"version":"3.51.4"},"reference-count":59,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T00:00:00Z","timestamp":1778284800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T00:00:00Z","timestamp":1778284800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Record"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The reported prevalence of feline idiopathic epilepsy (IE) and presumptive imaging diagnoses based on magnetic resonance imaging (MRI) varies depending on factors such as differences between primary care versus referral study populations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective, imaging\u2010based study reviewed MRI data from cats with suspected epileptic seizures. Cases were categorised as follows: no lesions detected (IE, referring to cats aged 6 months\u20127 years with recurrent epileptic seizures, and epilepsy or epileptic seizure of unknown aetiology [EuA] [i.e., cats not fulfilling IE criteria]) and structural lesion(s) detected (SL). Presumptive imaging diagnoses were classified according to the following aetiologies: presumptive intra\u2010axial\/extra\u2010axial neoplasia, inflammatory, vascular, congenital, traumatic, metabolic\/toxic and degenerative.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 432 MRIs, 39% revealed SL, whereas 61% showed no structural lesions (of which 47% of cases were classified as IE and 53% were classified as EuA). Among cats with SL, presumptive imaging\u2010based diagnoses included inflammatory diseases (25%), extra\u2010axial neoplasia (19%), metabolic\/toxic aetiologies (12%), congenital disorders (10%), lesions of unknown relevance (9%), intra\u2010axial neoplasia (7%), trauma (5%), suspected hippocampal necrosis (5%), vascular events (4%), thiamine deficiency (2%) and degenerative diseases (2%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Limitations<\/jats:title>\n                    <jats:p>This imaging\u2010based study lacked histopathological confirmation and comprehensive clinical information.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Nearly two\u2010thirds of MRIs involving cats with suspected epileptic seizures showed no structural brain abnormalities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/vetr.70737","type":"journal-article","created":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T12:39:42Z","timestamp":1778330382000},"source":"Crossref","is-referenced-by-count":0,"title":["Epidemiological distribution of MRI\u2010based presumptive imaging diagnoses in a large general population of cats with suspected epileptic seizures"],"prefix":"10.1002","author":[{"given":"Anna","family":"Knebel","sequence":"first","affiliation":[{"name":"Department of Small Animal Medicine &amp; Surgery University of Veterinary Medicine Hannover  Hannover Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2786-8454","authenticated-orcid":false,"given":"Sebastian","family":"Meller","sequence":"additional","affiliation":[{"name":"Department of Small Animal Medicine &amp; Surgery University of Veterinary Medicine Hannover  Hannover Germany"},{"name":"Center for Systems Neuroscience Hannover (ZSN)  Hannover Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julien","family":"Labruy\u00e8re","sequence":"additional","affiliation":[{"name":"VetCT  Cambridge UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7312-638X","authenticated-orcid":false,"given":"Holger A.","family":"Volk","sequence":"additional","affiliation":[{"name":"Department of Small Animal Medicine &amp; Surgery University of Veterinary Medicine Hannover  Hannover Germany"},{"name":"Center for Systems Neuroscience Hannover (ZSN)  Hannover Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,5,9]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.233.10.1591"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X18791873"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2017.04.001"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2010.07.001"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12917\u2010015\u20100461\u20102"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2013.04.008"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.104142"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.12297"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/inpract.27.4.208"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12917\u2010015\u20100462\u20101"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.j2896"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2009.03.006"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2004.225.1723"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.12250"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2011.05.014"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.15881"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prevetmed.2010.01.007"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.105647"},{"key":"e_1_2_11_20_1","doi-asserted-by":"crossref","unstructured":"Mai W. 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