{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T23:29:29Z","timestamp":1791588569720,"version":"4.3.4"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,11,24]],"date-time":"2022-11-24T00:00:00Z","timestamp":1669248000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp;amp; Sci"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Early detection of\n                      <jats:italic>Rhodococcus equi<\/jats:italic>\n                      pneumonia in foals is essential for horse health and for veterinarians.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aimed to demonstrate the usefulness of assessing the serum concentration of acute\u2010phase proteins (APPs) in the early diagnosis of pneumonia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The study evaluated APPs in 19 Arabian foals with\n                      <jats:italic>R. equi<\/jats:italic>\n                      pneumonia and compared them with 18 normal Arabian foals in equestrian clubs in Tabriz, Iran. Affected foals were identified through history, clinical findings and bacterial culture of tracheal washing. Biochemical methods and polymerase chain reaction tests were performed by examining the\n                      <jats:italic>16S rRNA<\/jats:italic>\n                      and\n                      <jats:italic>vapA<\/jats:italic>\n                      genes to confirm the diagnosis of bacterial isolates. Blood samples were taken from all sick and healthy horses, and their serum was isolated. APPs in the serum were measured in all the samples.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Rhodococcosis increased the serum concentration of haptoglobin (Hp) and serum amyloid A (SAA) (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001). The relationship between SAA and Hp was meaningful in the infected group (\n                      <jats:italic>r<\/jats:italic>\n                      = 0.933) but not in the healthy group. In cases where there are clinical findings of\n                      <jats:italic>R. equi<\/jats:italic>\n                      pneumonia, the concentration of SAA and Hp can help the effectiveness of treatment.\u2010\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Serum concentration analysis of APPs can be helpful in early diagnosis and successfully treating foals with\n                      <jats:italic>R. equi<\/jats:italic>\n                      pneumonia.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/vms3.1005","type":"journal-article","created":{"date-parts":[[2022,11,24]],"date-time":"2022-11-24T16:14:20Z","timestamp":1669306460000},"page":"144-149","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Evaluation of serum concentration of acute\u2010phase proteins (haptoglobin and serum amyloid A) in the affected Arabian foals with rhodococcosis"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0190-8152","authenticated-orcid":false,"given":"Ali","family":"Hassanpour","sequence":"first","affiliation":[{"name":"Department of Clinical Science Tabriz Medical Sciences Branch Islamic Azad University  Tabriz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sina","family":"Moghaddam","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Faculty of Veterinary Medicine University of Tehran  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,11,24]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.243.1.113"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetimm.2011.06.037"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2004.01.013"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.15.1.69"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2003.223.1791"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/cwi067"},{"issue":"1","key":"e_1_2_12_8_1","first-page":"14","article-title":"Treating foals with Rhodococcus equi infection: What do you recommend?","volume":"1","author":"Cohen N. 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