{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:15:35Z","timestamp":1772118935973,"version":"3.50.1"},"reference-count":39,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,7,7]],"date-time":"2023-07-07T00:00:00Z","timestamp":1688688000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp; Sci"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This article is a preliminary study to compare the ability of 0.05% chlorhexidine diacetate (CD) and 1% povidone\u2010iodine (PI) solutions to reduce bacterial contamination on the canine external ear canal during initial patient preparation and comparison of the incidence of immediate tissue reactions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study design<\/jats:title>\n                    <jats:p>The study is a multi\u2010institutional, randomised, clinical prospective study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals or sample population<\/jats:title>\n                    <jats:p>\n                      Dogs (\n                      <jats:italic>n<\/jats:italic>\n                      = 19) undergoing total ear canal ablation with bulla osteotomy (TECABO).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The external ear of each dog was cleaned with the assigned antiseptic solution. Culture of the ear was performed by standard techniques to semi\u2010quantitatively evaluate bacterial growth and to identify bacterial organisms pre\u2010 and post\u2010antiseptic use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Both antiseptic groups showed a significant reduction in bacterial growth score (BGS) between pre\u2010 and post\u2010antiseptic use (CD\n                      <jats:italic>p<\/jats:italic>\n                      = 0.009, PI p = 0.005). There was no difference in the reduction of BGS between CD and PI solutions (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.53). Minor adverse skin reactions occurred in 25% of cases. There was no significant difference in the occurrence of adverse skin reactions between antiseptics (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.63).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>CD and PI were similarly able to decrease the number of bacteria on the external ear following initial preparation. No difference in the incidence of adverse tissue reactions was found.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical significance<\/jats:title>\n                    <jats:p>Properly diluted aqueous formulations of either antiseptic may be used for safe preparation limited to the external ear canal of dogs. Additional studies evaluating outcomes such as duration of bacterial inhibition and incidence of surgical site infections are needed to fully elucidate differences between CD and PI antiseptics prior to TECABO.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/vms3.1200","type":"journal-article","created":{"date-parts":[[2023,7,7]],"date-time":"2023-07-07T13:10:34Z","timestamp":1688735434000},"page":"1998-2005","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effectiveness of chlorhexidine diacetate and povidone\u2010iodine in antiseptic preparation of the canine external ear canal prior to total ear canal ablation with bulla osteotomy procedure: A preliminary study"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1559-1574","authenticated-orcid":false,"given":"Alicia K.","family":"Nye","sequence":"first","affiliation":[{"name":"Department of Small Animal Clinical Sciences College of Veterinary Medicine and Biomedical Sciences, Texas A&amp;M University College Station Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Artem","family":"Rogovskyy","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathobiology College of Veterinary Medicine and Biomedical Sciences, Texas A&amp;M University College Station Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew A.","family":"Lazarus","sequence":"additional","affiliation":[{"name":"Dallas Veterinary Surgical Center Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riley","family":"Amore","sequence":"additional","affiliation":[{"name":"Dallas Veterinary Surgical Center Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelley M. 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