{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T14:36:48Z","timestamp":1767969408410,"version":"3.49.0"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006280","name":"Ministerio de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["BS\u201056\/2021\u201022"],"award-info":[{"award-number":["BS\u201056\/2021\u201022"]}],"id":[{"id":"10.13039\/501100006280","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp;amp; Sci"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Medicinal plants or their products are popular substitutes for antibiotics or other synthetic growth promoters for their beneficial effects and cost\u2010effectiveness. Clove (Cv) and tulsi (Ts) are rich in phytochemicals and are used to augment the growth performance of poultry.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The current investigation was carried out to evaluate the effects of Cv and Ts supplementation in drinking water on the morphologic and morphometric adaptations in the lymphoid organs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The experiment was conducted on 60 broiler chicks, divided into 4 homogenous groups (5 pens\/group and 3 broilers\/pen) named T0 (control), T1 (0.5% Cv and 2% Ts), T2 (1% Cv and 3% Ts) and T3 (1.5% Cv and 4% Ts). The treatments were administered from days 8 to 28. Lymphoid organs (thymus, spleen and bursa of Fabricius) were collected on days 14, 21 and 28 after sacrificing five broilers from each group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The treatment groups had higher thymus and spleen weights on day 21, whereas the weights of the bursa of Fabricius were higher on days 14, 21 and 28. In the histomorphologic study, no noticeable difference in the histoarchitectures of the lymphoid organs was noticed. However, substantial differences in the cortico\u2010medullary ratio and the number of follicles in the thymus and bursa of Fabricius, respectively, were found in the histomorphometric investigation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The inclusion of Cv and Ts in drinking water augments the weight of lymphoid organs with histomorphometric adaptations that might improve the immune status in broilers.<\/jats:p><\/jats:sec>","DOI":"10.1002\/vms3.1250","type":"journal-article","created":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T08:15:10Z","timestamp":1693556110000},"page":"2731-2738","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Efficacy of clove and tulsi supplementation in drinking water in broiler immunity"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6765-2693","authenticated-orcid":false,"given":"Rafiqul","family":"Islam","sequence":"first","affiliation":[{"name":"Department of Anatomy and Histology Faculty of Veterinary Science Bangladesh Agricultural University  Mymensingh Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5498-1017","authenticated-orcid":false,"given":"Nasrin","family":"Sultana","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Histology Faculty of Veterinary Science Bangladesh Agricultural University  Mymensingh Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,9]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.3329\/bjvm.v4i2.1289"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom10020202"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2944"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anifeedsci.2017.12.003"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2221\u20101691(14)60215\u2010X"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3923\/ijp.2015.152.176"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/japr\/13.1.86"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.5455\/vetworld.2013.172\u2010179"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.14202\/vetworld.2021.2889\u20102906"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11694\u2010021\u201000915\u20109"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/vms3.226"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psj.2022.101904"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psj.2022.102266"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-407160-5.00017-8"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12967\u2010018\u20101381\u20102"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.5455\/ajvs.272231"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani11030845"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1751731117003731"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1515\/biolog\u20102016\u20100137"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0043933917000071"},{"key":"e_1_2_10_22_1","first-page":"1","article-title":"Morphometric characterization of Ross line broiler chickens lymphoid organs reared under field conditions in Zulia state","volume":"14","author":"Perozo F.","year":"2004","journal-title":"Revista Cientifica de la Facultad de Ciencias Veterinarias"},{"issue":"2","key":"e_1_2_10_23_1","first-page":"101","article-title":"Involution of the thymus: A possible diagnostic pitfall","volume":"48","author":"Raica M.","year":"2007","journal-title":"Romanian Journal of Morphology and Embryology"},{"issue":"7","key":"e_1_2_10_24_1","first-page":"308","article-title":"Ocimum sanctum ameliorate anti\u2010oxidant, anti\u2010microbial and immune system for the control of diabetes against coronavirus: An episode","volume":"8","author":"Savita K. 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