{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T09:33:24Z","timestamp":1782812004533,"version":"3.54.5"},"reference-count":43,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T00:00:00Z","timestamp":1697500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp;amp; Sci"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Microorganisms living in the oral cavity play an important role in health and disease of the host. Cats are susceptible to oral infections, and it is documented that fungi in the oral cavity could impact these infections. Antifungal resistance has been increasing in recent years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study was designed to identify yeast isolates from the oral cavity of healthy cats and to evaluate their antifungal susceptibility pattern.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Oral specimens were collected from 60 cats and cultured at 37\u00b0C for 10 days. Yeasts were isolated and identified. Their antifungal susceptibility pattern was determined according to CLSI M44\u2010A.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Three yeast genera were isolated, including\n                      <jats:italic>Candida<\/jats:italic>\n                      spp (55.5%),\n                      <jats:italic>Rhodotorula<\/jats:italic>\n                      spp (33.3%) and\n                      <jats:italic>Hanseniaspora<\/jats:italic>\n                      spp (11.1%). Antifungal susceptibility profiling showed that, apart from a dose\u2010dependent effect of itraconazole,\n                      <jats:italic>Hanseniaspora<\/jats:italic>\n                      spp was susceptible to all seven drugs studied. The\n                      <jats:italic>Candida<\/jats:italic>\n                      species were susceptible to all drugs except ketoconazole (sensitivity 80%) and caspofungin (sensitivity 40%). In\n                      <jats:italic>R. glutinis<\/jats:italic>\n                      and\n                      <jats:italic>R. minuta<\/jats:italic>\n                      , 100% sensitivity was observed for amphotericin B, posaconazole, ketoconazole and voriconazole.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The results suggest that, in comparison with humans and other animals, cats have a different oral mycoflora in terms of species, number and diversity. However, these isolates have similar susceptibility patterns to those seen in isolates from other animals and humans. More studies should be done to further characterize the oral mycobiota of cats and its role in oral infections.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/vms3.1280","type":"journal-article","created":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T12:39:43Z","timestamp":1697546383000},"page":"2414-2419","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Antifungal susceptibility profile of yeasts isolated from the oral cavity of cats"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2333-3361","authenticated-orcid":false,"given":"Donya","family":"Nikaein","sequence":"first","affiliation":[{"name":"Mycology Research Center, Faculty of Veterinary Medicine University of Tehran  Tehran Iran"},{"name":"Department of Microbiology and Immunology, Faculty of Veterinary Medicine University of Tehran  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dariush","family":"Shirani","sequence":"additional","affiliation":[{"name":"Department of Small Animal Internal Medicine, Faculty of Veterinary Medicine University of Tehran  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aghil","family":"Sharifzadeh","sequence":"additional","affiliation":[{"name":"Mycology Research Center, Faculty of Veterinary Medicine University of Tehran  Tehran Iran"},{"name":"Department of Microbiology and Immunology, Faculty of Veterinary Medicine University of Tehran  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ava","family":"Alavi","sequence":"additional","affiliation":[{"name":"Mycology Research Center, Faculty of Veterinary Medicine University of Tehran  Tehran Iran"},{"name":"Department of Microbiology and Immunology, Faculty of Veterinary Medicine University of Tehran  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6777-5930","authenticated-orcid":false,"given":"Ali Reza","family":"Khosravi","sequence":"additional","affiliation":[{"name":"Mycology Research Center, Faculty of Veterinary Medicine University of Tehran  Tehran Iran"},{"name":"Department of Microbiology and Immunology, Faculty of Veterinary Medicine University of Tehran  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,10,17]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2021.105183"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0103\u201084781998000300015"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.14875"},{"issue":"7","key":"e_1_2_12_5_1","first-page":"341","article-title":"Bacteriology and mycology of otitis externa in dogs","volume":"134","author":"Bornand V.","year":"1992","journal-title":"Schweizer Archiv f\u00fcr Tierheilkunde"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1517\u201074912003000300004"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0103\u201084782005000200022"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.4067\/S0301\u2010732\ufffd;2007000200009"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a019752"},{"issue":"11","key":"e_1_2_12_10_1","first-page":"1445","article-title":"Caspofungin","volume":"16","author":"Deresinski S. 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