{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:15:51Z","timestamp":1772118951470,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T00:00:00Z","timestamp":1698624000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004481","name":"University of Tehran","doi-asserted-by":"publisher","award":["28786"],"award-info":[{"award-number":["28786"]}],"id":[{"id":"10.13039\/501100004481","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp;amp; Sci"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Congenital entropion is the most frequent ocular disorder in newborn lambs of certain sheep breeds, which, if not treated, can result in complete blindness and death due to starvation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The aims of this study were to compare the spontaneous healing of entropion in two breeds and assess the outcome of cases with and without therapeutic intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 158 entropion cases (119 Ile de France and 39 Romane) were investigated, and swab samples were collected from the cornea and conjunctiva of 73 of the affected lambs for bacteriological investigation. In addition, an ocular intervention was carried out in 123 affected animals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The Romane breed developed entropion at an average age of 7 days compared to the Ile de France, which developed it at an average age of 1 day. Likewise, significant differences were found between bilateral and unilateral involvement in both breeds. Meanwhile, 22.1% of cases recovered spontaneously, and the highest rate of spontaneous recovery without intervention was observed in the Romane breed (66%). Bacteria isolated from ocular samples included\n                      <jats:italic>Staphylococcus<\/jats:italic>\n                      spp. (42.5%),\n                      <jats:italic>Bacillus<\/jats:italic>\n                      spp. (21.9%),\n                      <jats:italic>Trueperella pyogenes<\/jats:italic>\n                      (13.7%),\n                      <jats:italic>Corynebacterium<\/jats:italic>\n                      spp. (12.3%) and\n                      <jats:italic>Escherichia coli<\/jats:italic>\n                      (9.6%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The results of the study showed that the onset time of entropion, bilateral involvement, the severity of the process and the need for re\u2010treatment were higher in the Ile de France breed than in the Romane breed. Likewise, the Romane breed showed a higher degree of spontaneous recovery of entropion.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/vms3.1317","type":"journal-article","created":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T07:35:49Z","timestamp":1698651349000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Comparison of entropion outcome with and without intervention in Romane and Ile de France sheep breeds"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6325-6984","authenticated-orcid":false,"given":"Hossein","family":"Esmaeili","sequence":"first","affiliation":[{"name":"Department of Microbiology and Immunology Faculty of Veterinary Medicine University of Tehran  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir Hossein","family":"Alinejad","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology Faculty of Veterinary Medicine University of Tehran  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mona","family":"Hamedi","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology Faculty of Veterinary Medicine University of Tehran  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6209-4282","authenticated-orcid":false,"given":"Sergio","family":"Villanueva\u2010Saz","sequence":"additional","affiliation":[{"name":"Department of Animal Pathology Veterinary Faculty University of Zaragoza  Zaragoza Spain"},{"name":"Instituto Agroalimentario de Arag\u00f3n\u2010IA2, Universidad de Zaragoza\u2010CITA  Zaragoza Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta Ruiz","family":"de Arcaute","sequence":"additional","affiliation":[{"name":"Department of Animal Pathology Veterinary Faculty University of Zaragoza  Zaragoza Spain"},{"name":"Instituto Agroalimentario de Arag\u00f3n\u2010IA2, Universidad de Zaragoza\u2010CITA  Zaragoza Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"P\u00e9rez","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Hospital Universitario Lozano Blesa  Zaragoza Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Iba\u00f1ez","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Hospital Universitario Lozano Blesa  Zaragoza Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7822-6646","authenticated-orcid":false,"given":"Delia","family":"Lacasta","sequence":"additional","affiliation":[{"name":"Department of Animal Pathology Veterinary Faculty University of Zaragoza  Zaragoza Spain"},{"name":"Instituto Agroalimentario de Arag\u00f3n\u2010IA2, Universidad de Zaragoza\u2010CITA  Zaragoza Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,10,30]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/1751\u20100147\u201045\u201019"},{"key":"e_1_2_11_3_1","first-page":"377","volume-title":"Essentials of veterinary ophtalmology","author":"Cameron J.","year":"2005"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smallrumres.2012.11.037"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.125.10.253"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.129.6.128"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0167\u20105877(95)00468\u2010C"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463\u20105224.2012.01061.x"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/age.12903"},{"key":"e_1_2_11_10_1","first-page":"345","article-title":"Temporary correction of entropion in young dogs","volume":"61","author":"Holmberg D.","year":"1980","journal-title":"Modern Veterinary Practice"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.239.4.486"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0196\u20109846(17)30011\u20103"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/vop.12348"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0196\u20109846(17)30015\u20100"},{"key":"e_1_2_11_15_1","volume-title":"Koneman's color atlas and textbook of diagnostic microbiology","author":"Procop G. 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