{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T03:34:52Z","timestamp":1792812892157,"version":"4.5.0"},"reference-count":77,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,8,13]],"date-time":"2024-08-13T00:00:00Z","timestamp":1723507200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,8,13]],"date-time":"2024-08-13T00:00:00Z","timestamp":1723507200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine & Sci"],"published-print":{"date-parts":[[2024,9]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Vitamin D possesses an important role in the maintenance and health of broiler chickens. Herbal essential oils (EOs) have been proposed as a suitable alternative to chemical drugs in intensive production management systems for better performance of broilers with slight side effects and admirable therapeutic properties.<\/jats:p>\n <\/jats:sec>\n \n Objectives<\/jats:title>\n \n This experiment was conducted to investigate the effects of feeding cholecalciferol (VD) in combination of\n Satureja rechingeri<\/jats:italic>\n EO (SREO) on growth performance, haematological indicators and immunological response of broilers.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A total of 540 1\u2010day\u2010old mixed\u2010sex broiler chickens (Ross 308) were used in a completely randomized design with a 3\u00a0\u00d7\u00a03 factorial arrangement of treatments. Experimental treatments included different concentrations of cholecalciferol (VD) (0, 2000 and 4000\u00a0IU\/kg\u00a0=\u00a00, 0.05 and 0.1\u00a0mg\/kg) and SREO (0, 200 and 400\u00a0mg\/kg) on growth performance, haematological indicators and immunological responses of broiler chickens were investigated.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The results showed that the chicken fed diet supplemented with 0.1\u00a0mg\/kg VD (VD\n 0.1<\/jats:sub>\n ) in combination of 200\u00a0mg\/kg SREO (SREO\n 200<\/jats:sub>\n ) increased the feed intake during the overall and first 14\u2010day periods of the trial when compared with other dietary treatments. Interaction of VD\n 0.1<\/jats:sub>\n \u00a0\u00d7\u00a0SREO\n 200<\/jats:sub>\n led to more body weight gain (BWG) in the grower and finisher phases than all other feed treatment groups. The blood level of lymphocyte at day 42, heterophil at days 28 and 42 and heterophil\/lymphocyte (H\/L) ratio at 14 and 28 days of age were affected by VD\n 0.1<\/jats:sub>\n \u00a0+\u00a0SREO\n 200<\/jats:sub>\n in comparison with VD\n 0<\/jats:sub>\n \u00a0+\u00a0SREO\n 0<\/jats:sub>\n group. Feeding VD and\/or SREO decreased triglyceride, cholesterol and low\u2010density lipoprotein concentrations at days 28 and 42 of the study, especially in VD\n 0.1<\/jats:sub>\n \u00a0+\u00a0SREO\n 200<\/jats:sub>\n treatment. Feeding VD\n 0.1<\/jats:sub>\n \u00a0+\u00a0SREO\n 200<\/jats:sub>\n also resulted in higher serum status of immunoglobulin M, lysozymes and phagocytic percentage among all treatments.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Considering the outcomes, it is suggested that the combination of suitable concentration of VD and EO of the plant had favourable effects on the immune system and performance criteria of broiler chickens.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/vms3.1587","type":"journal-article","created":{"date-parts":[[2024,8,13]],"date-time":"2024-08-13T09:18:56Z","timestamp":1723540736000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Cholecalciferol combined with\n Satureja rechingeri<\/i>\n essential oils improves growth performance and immune response of broiler chickens"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-9594-4432","authenticated-orcid":false,"given":"Morteza","family":"Taghizadeh","sequence":"first","affiliation":[{"name":"Koohrang Nature's Gold (KNG) Company Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5570-4353","authenticated-orcid":false,"given":"Hassan","family":"Esmaeili","sequence":"additional","affiliation":[{"name":"Department of Agriculture Medicinal Plants and Drugs Research Institute Shahid Beheshti University Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0011-2219","authenticated-orcid":false,"given":"Reza","family":"Vakili","sequence":"additional","affiliation":[{"name":"Department of Animal Science Kashmar Branch Islamic Azad University Kashmar Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,8,13]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.5829\/idosi.bjps.2013.2.2.74145"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani11123471"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.5713\/ajas.2013.13644"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.5923\/j.ijaf.20180806.03"},{"issue":"2","key":"e_1_2_11_6_1","first-page":"321","article-title":"Performance, morphological responses of the small intestine, and humoral immunity of broilers fed oak acorn (Quercus brantii) as a substitution for antibiotic growth promoters","volume":"13","author":"Afiouni A.","year":"2023","journal-title":"Iranian Journal of Applied Animal Science"},{"key":"e_1_2_11_7_1","first-page":"1288","article-title":"Effect of dietary thyme (Thymus vulgaris) and mint (Menthe piperita) on some blood parameters of broiler chickens","volume":"1","author":"Aghazadeh A.","year":"2011","journal-title":"Journal of Agricultural Science and Technology A"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1590\/1806-9061-2021-1534"},{"issue":"4","key":"e_1_2_11_9_1","first-page":"169","article-title":"Influence of two plant extracts derived from thyme and cinnamon on broiler performance","volume":"29","author":"Al\u2010Kassie G. 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