{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:13:22Z","timestamp":1772118802367,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,6,23]],"date-time":"2020-06-23T00:00:00Z","timestamp":1592870400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp; Sci"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Congenital heart disease is relatively uncommon in horses. Only three reports exist that describe a tetralogy of Fallot in adult horses. Whereas in humans the presence of congenital heart disease constitutes a risk factor for developing aortic aneurysms, their association has never been reported in horses. Here, we present a case with a large ascending aortic aneurysm as a complication of a tetralogy of Fallot in an adult mare. The mare was referred with sustained tachycardia and a 5\u00a0days history of mild intermittent colic, depression, inappetence and weight loss. Echocardiography was used to characterize the cardiac abnormalities and aortic root dilation. Due to the poor prognosis, the mare was euthanized and\n                    <jats:italic>post\u2010mortem<\/jats:italic>\n                    examination further characterized the abnormalities. At least four factors contributed in this case to the development of aortic haematoma: congenital disease, mucoid extracellular matrix accumulation\n                    <jats:italic>vasa vasorum<\/jats:italic>\n                    dysfunction and inflammatory\/degenerative lesions in the aorta's intima. Although colic is primarily caused by gastrointestinal issues, cardiac disease should be suspected in cases with sustained tachycardia, even in absence of murmurs or arrhythmias. Despite the fact that congenital abnormalities are usually detected in foals, they may sometimes remain unnoticed for several years.\n                  <\/jats:p>","DOI":"10.1002\/vms3.311","type":"journal-article","created":{"date-parts":[[2020,6,23]],"date-time":"2020-06-23T06:23:03Z","timestamp":1592893383000},"page":"9-15","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Ascending aortic aneurysm associated with tetralogy of Fallot in an adult mare"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2273-5377","authenticated-orcid":false,"given":"Valentina","family":"Vitale","sequence":"first","affiliation":[{"name":"University Teaching Hospital Sydney School of Veterinary Science University of Sydney Camden New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0689-7141","authenticated-orcid":false,"given":"Gaby","family":"Van Galen","sequence":"additional","affiliation":[{"name":"University Teaching Hospital Sydney School of Veterinary Science University of Sydney Camden New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malene","family":"Laurberg","sequence":"additional","affiliation":[{"name":"University Teaching Hospital Sydney School of Veterinary Science University of Sydney Camden New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bridgette","family":"Young","sequence":"additional","affiliation":[{"name":"University Teaching Hospital Sydney School of Veterinary Science University of Sydney Camden New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victoria","family":"Mciver","sequence":"additional","affiliation":[{"name":"University Teaching Hospital Sydney School of Veterinary Science University of Sydney Camden New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Wereszka","sequence":"additional","affiliation":[{"name":"University Teaching Hospital Sydney School of Veterinary Science University of Sydney Camden New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7368-6646","authenticated-orcid":false,"given":"Marina","family":"Gimeno","sequence":"additional","affiliation":[{"name":"University Teaching Hospital Sydney School of Veterinary Science University of Sydney Camden New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,6,23]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.735274"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2018.00124"},{"key":"e_1_2_7_4_1","first-page":"411","article-title":"Tetralogy of Fallot and segmental uterine aplasia in a three\u2010year\u2010old Morgan filly","volume":"81","author":"Cargile J.","year":"1991","journal-title":"Cornell Veterinarian"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cveq.2018.12.005"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.21836\/PEM20060403"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2009.0445.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carpath.2016.03.002"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1983.tb01826.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvc.2017.10.005"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvc.2016.04.002"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.116.307909"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-7020-2817-5.00014-6"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.1998.tb00321.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjcr\/ytz053"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.2012.00580.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/0300985814528219"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.12340"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.77.5.534"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cveq.2018.11.001"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1556\/004.2016.033"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.253.12.1551"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/030098588502200108"}],"container-title":["Veterinary Medicine and Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fvms3.311","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/vms3.311","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/vms3.311","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/vms3.311","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T14:22:37Z","timestamp":1693750957000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/vms3.311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,23]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1002\/vms3.311"],"URL":"https:\/\/doi.org\/10.1002\/vms3.311","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1002\/VMS3.311\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.311\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.311\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.311\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.311\/v2\/response1","asserted-by":"object"}]},"ISSN":["2053-1095","2053-1095"],"issn-type":[{"value":"2053-1095","type":"print"},{"value":"2053-1095","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,23]]},"assertion":[{"value":"2019-12-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}