{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T18:37:58Z","timestamp":1790620678376,"version":"4.1.0"},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,9,23]],"date-time":"2020-09-23T00:00:00Z","timestamp":1600819200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp;amp; Sci"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The intravenous (IV) usage of diuretic agents such as furosemide may cause changes in clinical signs, electrocardiographic (ECG) indices and serum electrolytes (sodium, potassium, chloride, calcium, phosphorus and magnesium) concentrations in dromedary calves. The purpose of this study was to evaluate the clinical, ECG and biochemical effects of two\u2010dose IV administration of furosemide in dromedary calves. A total of 21 clinically healthy male dromedary calves with the age of 5 (\u00b1 1) months and weight of 95 (\u00b1 5) kg were studied. The animals were randomly divided into three groups of control (normal saline), low\u2010dose furosemide (2.5\u00a0mg\/kg) and high\u2010dose furosemide (5\u00a0mg\/kg). Two IV injections with 12\u2010hr intervals were administered in all animals. The clinical and ECG parameters were measured at 0 (baseline), 2 (T2), 24 (T24) and 48 (T48) hours after drug administration. Serum concentrations of electrolytes were measured at T0, T24 and T48 hr. The results of this study showed no changes in clinical parameters (heart rate, rectal temperature, respiratory rate and Unruminal motility), ECG indices and also no significant changes in serum electrolytes levels. Under conditions with free access to fresh water, two\u2010dose IV injection of furosemide (2.5 and 5\u00a0mg\/kg) could be administered in healthy dromedary calves.<\/jats:p>","DOI":"10.1002\/vms3.365","type":"journal-article","created":{"date-parts":[[2020,9,23]],"date-time":"2020-09-23T16:20:36Z","timestamp":1600878036000},"page":"1185-1190","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Effects of two\u2010dose intravenous administration of furosemide on clinical variables, electrocardiographic indices and serum electrolytes in dromedary calves"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4568-6619","authenticated-orcid":false,"given":"Amir Saeed","family":"Samimi","sequence":"first","affiliation":[{"name":"Department of Clinical Science Faculty of Veterinary Medicine Shahid Bahonar University of Kerman Kerman Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Sanjarinejad","sequence":"additional","affiliation":[{"name":"Department of Clinical Science Faculty of Veterinary Medicine Shahid Bahonar University of Kerman Kerman Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,9,23]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-0736(98)90006-1"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2885.1997.00088.x"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0034-5288(98)90118-7"},{"key":"e_1_2_9_5_1","first-page":"46","article-title":"Furosemide induced electrocardiographic alterations in high producing Holstein dairy cows","volume":"1","author":"Chalmeh A.","year":"2016","journal-title":"Iranian Journal of Ruminants Health Research"},{"key":"e_1_2_9_6_1","volume-title":"Veterinary medicine: A text book of the diseases of cattle, horses, sheep, pigs and goats","author":"Constable P. 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