{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:15:44Z","timestamp":1772118944618,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,9,29]],"date-time":"2020-09-29T00:00:00Z","timestamp":1601337600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp;amp; Sci"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>A 20\u2010year\u2010old grey Warmblood gelding that had history of dermal melanomatosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To report surgical treatment of a 6\u2010cm large malignant metastatic melanoma located in the cutaneous trunci muscle of the left lateral thorax of a horse.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A 20\u2010year\u2010old grey Warmblood gelding was referred for evaluation of a large, rapidly growing, thoracic mass. Clinical examination revealed an ovoid, firm, non\u2010painful, movable mass, approximately 6\u00a0cm in diameter, located in the cutaneous trunci muscle of the left lateral thorax. Multiple melanocytic nodules were also found at the perianal region and ventral tail. Rectal examination, ultrasonography and endoscopy of the respiratory tract revealed no melanomas internally. Haematological and biochemical values were within normal limits. Surgical excision of both the thoracic mass and perianal nodules was the treatment of choice. Histopathology of the distant thoracic mass confirmed the diagnosis of malignant metastatic melanoma secondary to the perineal lesions that were confirmed as dermal melanomatosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The horse recovered uneventfully. Up until 3\u00a0years post surgery there was no tumour regrowth at the excision sites.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Surgical excision of the metastatic melanoma was performed and considered successful, with no gross evidence of tumour reoccurrence. Despite the fact that surgical excision is considered a treatment option regarding equine dermal melanomatosis, there is no previously published study proposing surgical removal of distant malignant metastatic melanocytic masses. This is the first report of a successful surgical excision of a large (6\u00a0cm) metastatic melanocytic tumour from the skeletal muscle of the lateral thorax of a horse.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/vms3.366","type":"journal-article","created":{"date-parts":[[2020,9,29]],"date-time":"2020-09-29T09:16:18Z","timestamp":1601370978000},"page":"297-302","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Surgical excision of a malignant metastatic melanoma located in a skeletal muscle of the lateral thorax of a horse"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5210-8492","authenticated-orcid":false,"given":"Theodora","family":"Billi","sequence":"first","affiliation":[{"name":"Faculty of Health Sciences Equine Unit School of Veterinary Medicine Aristotle University of Thessaloniki Thessaloniki Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasiliki","family":"Karadima","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences Equine Unit School of Veterinary Medicine Aristotle University of Thessaloniki Thessaloniki Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2325-3791","authenticated-orcid":false,"given":"Panagiota","family":"Tyrnenopoulou","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences Equine Unit School of Veterinary Medicine Aristotle University of Thessaloniki Thessaloniki Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanouela P.","family":"Apostolopoulou","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences Laboratory of Pathology School of Veterinary Medicine Aristotle University of Thessaloniki Thessaloniki Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgia D.","family":"Brellou","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences Laboratory of Pathology School of Veterinary Medicine Aristotle University of Thessaloniki Thessaloniki Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikolaos","family":"Diakakis","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences Equine Unit School of Veterinary Medicine Aristotle University of Thessaloniki Thessaloniki Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,9,29]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jevs.2013.11.012"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.164.9.278"},{"key":"e_1_2_14_4_1","doi-asserted-by":"crossref","first-page":"449","DOI":"10.2460\/javma.1990.196.03.449","article-title":"Cimetidine for treatment of melanoma in three horses","volume":"196","author":"Goetz T. E.","year":"1990","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/eve.12767"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.229.10.1617"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-0739(17)30190-6"},{"key":"e_1_2_14_8_1","first-page":"1215","article-title":"Pelvic limb lameness due to malignant melanoma in a horse","volume":"86","author":"Kirker\u2010Head C. A.","year":"1985","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-7020-4266-9.00013-1"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0368-1742(33)80025-7"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2002.tb01264.x"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2002.220.1192"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3292.2011.00368.x"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/CJI.0b013e3181fe1997"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1053\/ctep.2002.33171"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2004.225.94"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.230.10.1506"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.1995.tb01087.x"}],"container-title":["Veterinary Medicine and Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/vms3.366","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/vms3.366","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/vms3.366","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T22:50:03Z","timestamp":1723675803000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/vms3.366"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,29]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1002\/vms3.366"],"URL":"https:\/\/doi.org\/10.1002\/vms3.366","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1002\/VMS3.366\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.366\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.366\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.366\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.366\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.366\/v1\/review2","asserted-by":"object"}]},"ISSN":["2053-1095","2053-1095"],"issn-type":[{"value":"2053-1095","type":"print"},{"value":"2053-1095","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,29]]},"assertion":[{"value":"2020-01-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-09","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}