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Fifty\u2010five neutropaenic dogs presenting to the University of Wisconsin Veterinary Medical Teaching Hospital were enrolled for a total of 57 neutropaenic episodes. The overall incidence of bacteraemia was 12.3% (<jats:italic>n<\/jats:italic>\u00a0=\u00a07\/57). Three afebrile dogs and four febrile dogs were bacteraemic; this difference was not significant (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.6968). The overall incidence of bacteruria was 7.5% (<jats:italic>n<\/jats:italic>\u00a0=\u00a04\/53). Two afebrile dogs and two febrile dogs were bacteruric; this difference was not significant (<jats:italic>P<\/jats:italic>\u00a0=\u00a01.0). Of the positive blood cultures, the majority of organisms cultured (<jats:italic>n<\/jats:italic>\u00a0=\u00a06\/7) were gram\u2010positive organisms with one gram\u2010negative organism. Three of the positive blood cultures showed<jats:italic>in\u00a0vitro<\/jats:italic>resistance to more than one antimicrobial agent. Clinical parameters (age, body weight, heart rate, rectal temperature, neutrophil count, haematocrit and platelet count) were not predictive of bacteraemia. The results of this study were not sufficient to justify the use of blood cultures as a first\u2010line diagnostic test for neutropaenic patients. Blood cultures may have utility in individual case management for a minority of patients in guiding antibiotic choice in the case of resistant bacterial infections. Blood cultures may serve as a tool for antimicrobial de\u2010escalation, although further study is needed.<\/jats:p>","DOI":"10.1002\/vms3.49","type":"journal-article","created":{"date-parts":[[2016,11,16]],"date-time":"2016-11-16T17:22:28Z","timestamp":1479316948000},"page":"281-294","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Prospective study evaluating the incidence of bacteraemia and bacteruria in afebrile and febrile neutropaenic dogs undergoing chemotherapy"],"prefix":"10.1002","volume":"2","author":[{"given":"Kimberly","family":"Shaffer","sequence":"first","affiliation":[{"name":"Department of Medical Sciences School of Veterinary Medicine Veterinary Medical Teaching Hospital University of Wisconsin\u2010Madison Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Bach","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences School of Veterinary Medicine Veterinary Medical Teaching Hospital University of Wisconsin\u2010Madison Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruthanne","family":"Chun","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences School of Veterinary Medicine Veterinary Medical Teaching Hospital University of Wisconsin\u2010Madison Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,11,14]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4557-0306-7.00091-X"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/vco.12001"},{"key":"e_1_2_10_4_1","doi-asserted-by":"crossref","first-page":"296","DOI":"10.2460\/javma.1978.173.03.296","article-title":"Comparison of collection techniques for quantitative urine culture in dogs","volume":"173","author":"Carter 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