{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T16:48:36Z","timestamp":1777481316910,"version":"3.51.4"},"reference-count":11,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,9,4]],"date-time":"2021-09-04T00:00:00Z","timestamp":1630713600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp; Sci"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Autoimmune polyendocrine syndrome, also called polyglandular autoimmune syndrome, is a rare immune\u2010mediated disorder that involves various endocrine glands.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To report autoimmune polyendocrine syndrome in a dog.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A 9\u2010year\u2010old spayed female miniature poodle diagnosed with insulin\u2010dependent diabetes mellitus emergently visited our clinic for anorexia, severe depression, and vomiting. Hyponatremia, hypochloridemia, and recurrent hypoglycaemia were found. Hypoadrenocorticism was diagnosed based on consistent clinical signs and repeated adrenocorticotropic hormone stimulation tests.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>After injecting deoxycorticosterone pivalate and increasing the oral prednisolone dose, the patient's systemic condition improved.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>To the best of our knowledge, this is the first case report of hypoadrenocorticism concurrent with diabetes mellitus in a dog. Furthermore, we would like to present the probability of an immune\u2010mediated disorder with multiple organs involved, like type IV autoimmune polyendocrine syndrome in humans.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/vms3.625","type":"journal-article","created":{"date-parts":[[2021,9,4]],"date-time":"2021-09-04T03:40:48Z","timestamp":1630726848000},"page":"2120-2123","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Autoimmune polyendocrine syndrome with hypoadrenocorticism and diabetes mellitus in a dog: A rare case"],"prefix":"10.1002","volume":"7","author":[{"given":"Seo\u2010Young","family":"Hwang","sequence":"first","affiliation":[{"name":"Labolatory of Veterinary Internal Medicine Department of Veterinary Clinical Science College of Veterinary Medicine and Research Institute for Veterinary Science Seoul National University  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ju\u2010Hyun","family":"An","sequence":"additional","affiliation":[{"name":"Labolatory of Veterinary Internal Medicine Department of Veterinary Clinical Science College of Veterinary Medicine and Research Institute for Veterinary Science Seoul National University  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeong\u2010Hwa","family":"Lee","sequence":"additional","affiliation":[{"name":"Labolatory of Veterinary Internal Medicine Department of Veterinary Clinical Science College of Veterinary Medicine and Research Institute for Veterinary Science Seoul National University  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Su\u2010Min","family":"Park","sequence":"additional","affiliation":[{"name":"Labolatory of Veterinary Internal Medicine Department of Veterinary Clinical Science College of Veterinary Medicine and Research Institute for Veterinary Science Seoul National University  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyung","family":"Kyu Chae","sequence":"additional","affiliation":[{"name":"Labolatory of Veterinary Internal Medicine Department of Veterinary Clinical Science College of Veterinary Medicine and Research Institute for Veterinary Science Seoul National University  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyung\u2010Bo","family":"Kim","sequence":"additional","affiliation":[{"name":"Labolatory of Veterinary Internal Medicine Department of Veterinary Clinical Science College of Veterinary Medicine and Research Institute for Veterinary Science Seoul National University  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9195-551X","authenticated-orcid":false,"given":"Woo\u2010Jin","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Veterinary Internal Medicine College of Veterinary Medicine and Research Institute of Veterinary Science Jeju National University  Jeju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0283-1348","authenticated-orcid":false,"given":"Hwa\u2010Young","family":"Youn","sequence":"additional","affiliation":[{"name":"Labolatory of Veterinary Internal Medicine Department of Veterinary Clinical Science College of Veterinary Medicine and Research Institute for Veterinary Science Seoul National University  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,9,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.238.12.1616"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.4158\/EP.14.6.750"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.5326\/JAAHA-MS-5745"},{"key":"e_1_2_8_5_1","first-page":"642","article-title":"Hypoglycemia in dogs: Causes, management, and diagnosis","volume":"59","author":"Idowu O.","year":"2018","journal-title":"Canadian Veterinary Journal"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/01652176.1995.9694533"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/pmj.76.894.230"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.4183\/aeb.2016.104"},{"key":"e_1_2_8_9_1","volume-title":"Small animal internal medicine\u2010E\u2010book","author":"Nelson R. 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