{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T01:57:47Z","timestamp":1789437467172,"version":"build-2803163510"},"reference-count":42,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,11,2]],"date-time":"2021-11-02T00:00:00Z","timestamp":1635811200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp; Sci"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Pigeon aviadenovirus A and Pigeon circovirus are both DNA viruses, infect and cause severe clinical diseases in pigeons. These viruses are associated with an immunosuppression syndrome similar to \u2018Young Pigeon Disease Syndrome\u2019 (YPDS). This study reports the identification of a natural co\u2010infection, with severe clinical signs (crop vomiting, watery diarrhoea, anorexia and sudden death) of Pigeon aviadenovirus A and Pigeon circovirus in a breeding pigeon flock in Central Anatolia, Turkey. Both viruses were isolated from pigeons pooled internal organs using primary chicken embryo kidney cell cultures (CEKC) and specific pathogen\u2010free (SPF) embryonated chicken eggs. Also, both viruses were identified by PCR amplification followed by Sanger sequencing whereas histopathological examination showed degenerated hepatocytes with basophilic intranuclear viral inclusions. As known, both viruses typically have similar transmission characteristics and common clinical manifestations; however, co\u2010infection may exacerbate the disease with devastating outcomes. This is the first report of its kind in Turkey for those viruses and is essential for the protection against these kinds of infections in pigeons.<\/jats:p>","DOI":"10.1002\/vms3.662","type":"journal-article","created":{"date-parts":[[2021,11,2]],"date-time":"2021-11-02T23:45:49Z","timestamp":1635896749000},"page":"139-149","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["First detection and molecular characterisation of a pigeon aviadenovirus A and pigeon circovirus co\u2010infection associated with Young Pigeon Disease Syndrome (YPDS) in Turkish pigeons (\n                    <i>Columba livia<\/i>\n                    domestica)"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7770-5082","authenticated-orcid":false,"given":"Ismail","family":"Sahindokuyucu","sequence":"first","affiliation":[{"name":"Poultry Diseases Diagnostic Laboratory, Bornova Veterinary Control Institute Ministry of Agriculture and Forestry Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merve Biskin","family":"Turkmen","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine Department of Veterinary Pathology, Kirikkale University Kirikkale Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tugce","family":"Sumer","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine Department of Veterinary Pathology, Kirikkale University Kirikkale Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0738-1825","authenticated-orcid":false,"given":"Ahmed Eisa","family":"Elhag","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine Department of Veterinary Virology, Ondokuz Mayis University Samsun Turkey"},{"name":"Faculty of Veterinary Sciences Department of Preventive Medicine and Clinical Studies, University of Gadarif Al Qadarif Sudan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet Eray","family":"Alcigir","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine Department of Veterinary Pathology, Kirikkale University Kirikkale Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2806-7878","authenticated-orcid":false,"given":"Zafer","family":"Yazici","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine Department of Veterinary Virology, Ondokuz Mayis University Samsun Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald","family":"Barry","sequence":"additional","affiliation":[{"name":"Veterinary Science Center, School of Veterinary Medicine University College of Dublin Belfield Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa Yavuz","family":"Gulbahar","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine Department of Veterinary Pathology, Ondokuz Mayis University Samsun Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oguz","family":"Kul","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine Department of Veterinary Pathology, Kirikkale University Kirikkale Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,11,2]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/03079450124811"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/03079459508419087"},{"key":"e_1_2_12_4_1","first-page":"13","article-title":"Les infections par ad\u00e9novirus chez le pigeon","volume":"144","author":"Duchatel J. 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