{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T15:44:18Z","timestamp":1783957458788,"version":"3.55.0"},"reference-count":31,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T00:00:00Z","timestamp":1744243200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T00:00:00Z","timestamp":1744243200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004481","name":"University of Tehran","doi-asserted-by":"publisher","award":["7405074\/12\/1400"],"award-info":[{"award-number":["7405074\/12\/1400"]}],"id":[{"id":"10.13039\/501100004481","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003968","name":"Iran National Science Foundation","doi-asserted-by":"publisher","award":["99022666"],"award-info":[{"award-number":["99022666"]}],"id":[{"id":"10.13039\/501100003968","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp;amp; Sci"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Eimeria maxima<\/jats:italic>\n                    is one of the seven\n                    <jats:italic>Eimeria<\/jats:italic>\n                    species that infect poultry. Despite being highly immunogenic, this species also displays variability in terms of antigenic characteristics. The objective of this study was to examine the biopathological properties of two distinct\n                    <jats:italic>Eimeria maxima<\/jats:italic>\n                    isolates in Iran. Two mixed field samples, collected from backyard poultry droppings with the highest numbers of\n                    <jats:italic>Eimeria maxima<\/jats:italic>\n                    oocysts, were selected for experimental challenges. The birds were inoculated with an equal number of oocysts, and the biopathological indicators of\n                    <jats:italic>Eimeria<\/jats:italic>\n                    oocysts were evaluated. The findings revealed that the two strains exhibited differences in terms of pathological lesions and intestinal inflammatory reactions on the seventh day post\u2010challenge (\n                    <jats:italic>p<\/jats:italic>\n                    &gt; 0.05). Consequently, it was demonstrated that\n                    <jats:italic>Eimeria maxima<\/jats:italic>\n                    isolates from geographically distant regions possessed biological and pathogenic dissimilarities.\n                  <\/jats:p>","DOI":"10.1002\/vms3.70235","type":"journal-article","created":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T04:23:06Z","timestamp":1744258986000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Intraspecific Variations in Biology and Pathogenesis of Two\n                    <i>Eimeria maxima<\/i>\n                    Isolates From Distinct Geographic Locations"],"prefix":"10.1002","volume":"11","author":[{"given":"Elham","family":"Sobhani","sequence":"first","affiliation":[{"name":"Department of Parasitology Faculty of Veterinary Medicine University of Tehran  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7579-0180","authenticated-orcid":false,"given":"Fatemeh","family":"Arabkhazaeli","sequence":"additional","affiliation":[{"name":"Department of Parasitology Faculty of Veterinary Medicine University of Tehran  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6498-2942","authenticated-orcid":false,"given":"Seyed Ahmad","family":"Madani","sequence":"additional","affiliation":[{"name":"Department of Animal and Poultry Health and Nutrition Faculty of Veterinary Medicine University of Tehran  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,10]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2023.110010"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-012-3041-4"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1590\/1678-5150-pvb-6968"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1637\/11518-102116-Reg.1"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2005.09.011"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13567-020-00837-2"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.3382\/ps\/pey587"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000063654"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psj.2019.10.028"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-407705-8.00002-1"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/9780470344620"},{"key":"e_1_2_9_13_1","doi-asserted-by":"crossref","unstructured":"Flores R. 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