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Although these parasites are generally considered a health threat in Asian countries, they are also present in various regions of T\u00fcrkiye and have been found in 12 different freshwater fish species commonly consumed in local cultures. However, their presence has not been reported in the endemic Anatolian fish, <jats:italic>Alburnus escherichii<\/jats:italic>. This study aims to determine the presence of clinostomid species in <jats:italic>A. escherichii<\/jats:italic> from the Sar\u0131su stream in Eski\u015fehir, T\u00fcrkiye.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>In addition to using a combination of ecological, morphological, molecular and histopathological approaches, our findings revealed the presence of <jats:italic>Clinostomum complanatum<\/jats:italic> within the branchial and buccal cavities of <jats:italic>A. escherichii<\/jats:italic>. Further histopathological examination revealed encysted metacercariae of <jats:italic>C. complanatum<\/jats:italic> invading the host tissues encapsulated within a thin fibrotic layer and accompanied by moderate inflammatory cell infiltration and degenerative changes in muscle cells.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These results provide new insights into the geographical and host distribution as well as histopathological impacts of <jats:italic>C. complanatum<\/jats:italic> metacercariae in teleost species.<\/jats:p><\/jats:sec>","DOI":"10.1002\/vms3.70270","type":"journal-article","created":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T10:19:42Z","timestamp":1742206782000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Ecological, Molecular, Histopathological and Public Health Implications of Zoonotic Metacercariae <i>Clinostomum complanatum<\/i> (Rudolphi, 1814) in the Endemic Anatolian Fish, <i>Alburnus escherichii<\/i>"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9926-166X","authenticated-orcid":false,"given":"Nurten","family":"Aydogdu","sequence":"first","affiliation":[{"name":"Department of Hydrobiology, Graduate School of Natural and Applied Sciences Bal\u0131kesir University  Bal\u0131kes\u0131r Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3881-095X","authenticated-orcid":false,"given":"Simonetta","family":"Mattiucci","sequence":"additional","affiliation":[{"name":"Department of Public Health and Infectious Diseases Section of Parasitology, Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4576-8892","authenticated-orcid":false,"given":"Marialetizia","family":"Palomba","sequence":"additional","affiliation":[{"name":"Department of Ecological and Biological Sciences (DEB) Tuscia University  Viterbo Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2778-0273","authenticated-orcid":false,"given":"Ali","family":"Aydogdu","sequence":"additional","affiliation":[{"name":"Department of Aquatic Animal Diseases, Faculty of Veterinary Medicine Bursa Uludag University  Bursa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0381-9321","authenticated-orcid":false,"given":"\u00c7i\u011fdem","family":"\u00dcrk\u00fc","sequence":"additional","affiliation":[{"name":"Faculty of Aquatic Sciences, Department of Fish Diseases Istanbul University  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7953-3245","authenticated-orcid":false,"given":"H. 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