{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T15:10:05Z","timestamp":1788966605073,"version":"build-2803163510"},"reference-count":58,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T00:00:00Z","timestamp":1746489600000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006261","name":"Taif University","doi-asserted-by":"publisher","award":["TU\u2010DSPP\u20102024\u201005"],"award-info":[{"award-number":["TU\u2010DSPP\u20102024\u201005"]}],"id":[{"id":"10.13039\/501100006261","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp;amp; Sci"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The rise of antibiotic resistance poses a significant challenge to veterinary medicine, particularly in the treatment of wound infections in animals. This study aimed to evaluate the antibacterial properties of traditional medicinal plants against four bacterial strains isolated from septic animal wound infections and to compare their effectiveness with broad\u2010spectrum antibiotics. A total of 150 bacterial isolates were collected using sterile cotton swabs, cultured on nutrient and mannitol salt agar for growth and identified through catalase and coagulase tests. The study assessed antibiotic resistance and tested the bacterial isolates\u2019 susceptibility to medicinal plants using the disc diffusion method. Among the isolates,\n                    <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    was the most common pathogen, accounting for 26.6% (40 isolates), followed by\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    at 26% (39 isolates).\n                    <jats:italic>Streptococcus<\/jats:italic>\n                    spp. and\n                    <jats:italic>Pseudomonas<\/jats:italic>\n                    spp. were found in 20% (30 isolates) and 16% (25 isolates), respectively. Antibiogram analysis revealed notable antibiotic resistance, with\n                    <jats:italic>S. aureus<\/jats:italic>\n                    showing the highest resistance to Ciprofloxacin (60.5%) and Rifampicin (57.5%).\n                    <jats:italic>E. coli<\/jats:italic>\n                    exhibited 61.5% resistance to Ciprofloxacin and 56.4% to streptomycin.\n                    <jats:italic>Streptococcus<\/jats:italic>\n                    spp. had the highest resistance to Ciprofloxacin (53.3%), whereas\n                    <jats:italic>Pseudomonas<\/jats:italic>\n                    spp. showed the greatest resistance to Chloramphenicol (52%). Ethanol extracts of the medicinal plants, prepared using various solvents, were utilized for testing. Ethanol extracts of\n                    <jats:italic>Loranthus acaciae<\/jats:italic>\n                    and\n                    <jats:italic>Cymbopogon proximus<\/jats:italic>\n                    at concentrations of 60\u201390\u00a0\u00b5L demonstrated the largest inhibition zones, ranging from 55.5\u00a0\u00b1\u00a03.85 to 57.5\u00a0\u00b1\u00a02.5\u00a0mm against\n                    <jats:italic>E. coli<\/jats:italic>\n                    and\n                    <jats:italic>S. aureus<\/jats:italic>\n                    . Inhibition zones for\n                    <jats:italic>Streptococcus<\/jats:italic>\n                    spp. and\n                    <jats:italic>Pseudomonas<\/jats:italic>\n                    spp. ranged from 50\u00a0\u00b1\u00a02 to 48.3\u00a0\u00b1\u00a01.7\u00a0mm. In comparison, the standard antibiotics exhibited inhibition zones of 58.95\u00a0\u00b1\u00a02.55\u201360\u00a0\u00b1\u00a02.5\u00a0mm against\n                    <jats:italic>S. aureus<\/jats:italic>\n                    and\n                    <jats:italic>E. coli<\/jats:italic>\n                    , with slightly lower zones (51.65\u00a0\u00b1\u00a01.6\u201349\u00a0\u00b1\u00a01\u00a0mm) observed for\n                    <jats:italic>Streptococcus<\/jats:italic>\n                    spp. and\n                    <jats:italic>Pseudomonas<\/jats:italic>\n                    spp. These findings underscore the significant antibacterial activity of medicinal plants against multidrug\u2010resistant pathogens in animal wound infections, highlighting their potential to accelerate healing, reduce infection severity and provide a cost\u2010effective alternative to combat antibiotic resistance.\n                  <\/jats:p>","DOI":"10.1002\/vms3.70361","type":"journal-article","created":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T07:10:22Z","timestamp":1747638622000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Antibacterial Activity of Traditional Medicinal Plants: Combating Antibiotics Resistance in Animal Wound Infections"],"prefix":"10.1002","volume":"11","author":[{"given":"Dan","family":"Jia","sequence":"first","affiliation":[{"name":"Outpatient Department West China Hospital, Sichuan University\/West China School of Nursing, Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9940-9708","authenticated-orcid":false,"given":"Safia","family":"Arbab","sequence":"additional","affiliation":[{"name":"Lanzhou Institute of Husbandry and Pharmaceutical Sciences Chinese Academy of Agricultural Sciences  Lanzhou 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