{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T13:14:27Z","timestamp":1774271667371,"version":"3.50.1"},"reference-count":43,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:00:00Z","timestamp":1745452800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:00:00Z","timestamp":1745452800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp;amp; Sci"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Primary mesenchymal tumours of the spleen in non\u2010human primates are exceedingly rare. We report on a 13\u2010year\u2010old female rhesus monkey who had an enlarged liver, spleen and multiple lung masses. Macroscopic, microscopic and immunohistochemical examinations revealed a splenic leiomyosarcoma with widespread metastasis. This is the first report of a splenic leiomyosarcoma in a non\u2010human primate.<\/jats:p>","DOI":"10.1002\/vms3.70378","type":"journal-article","created":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T13:39:54Z","timestamp":1745501994000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Primary Splenic Leiomyosarcoma With Metastasis in a Rhesus Monkey (\n                    <i>Macaca mulatta<\/i>\n                    )"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6234-4875","authenticated-orcid":false,"given":"Matthew F.","family":"Starost","sequence":"first","affiliation":[{"name":"Office of Research Services Division of Veterinary Resources National Institutes of Health  Bethesda Maryland USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,4,24]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"82","article-title":"Leiomyosarcoma of the Splenic Vein","volume":"10","author":"Akhaladze G. G.","year":"2019","journal-title":"Khirurgiia"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1746-6148-8-97"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/PL00008213"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0684.1989.tb00410.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0684.1996.tb00030.x"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0684.1998.tb00082.x"},{"key":"e_1_2_9_8_1","first-page":"70","article-title":"Abdominal Leiomyosarcoma in a Rhesus Macaque","volume":"34","author":"Bradfield J. F.","year":"1995","journal-title":"Contemporary Topics in Laboratory Animal Science"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/030098589002700210"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/030098588902600415"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000001795"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0684.2005.00092.x"},{"key":"e_1_2_9_13_1","first-page":"47","article-title":"Spontaneous Uterine Leiomyosarcoma in a Rhesus Monkey","volume":"43","author":"Cook A. L.","year":"2004","journal-title":"Contemporary Topics in Laboratory Animal Science"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1067\/msy.2001.111706"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(97)90324-9"},{"issue":"4","key":"e_1_2_9_16_1","first-page":"250","article-title":"Splenic Masses in Dogs. Part 1: Epidemiologic, Clinical Characteristics as Well as Histopathologic Diagnosis in 249 Cases (2000\u20132011)","volume":"40","author":"Eberle N.","year":"2012","journal-title":"Tierarztl Prax Ausg K Kleintiere Heimtiere"},{"key":"e_1_2_9_17_1","first-page":"144","article-title":"Leiomyosarcoma of the Spleen in a Bovine","volume":"4","author":"Feldman W. H.","year":"1928","journal-title":"American Journal of Pathology"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2011.09.053"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1638\/2016-0171R1.1"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0684.2010.00425.x"},{"key":"e_1_2_9_21_1","first-page":"193","article-title":"Primary Splenic Lymphoma","volume":"30","author":"Isaacson P. G.","year":"1997","journal-title":"Cancer Surveys"},{"key":"e_1_2_9_22_1","first-page":"60","article-title":"Leiomyosarcoma of the Uterus in a Rhesus Monkey With Iliac Lymph Node Metastasis, Endosalpingosis, and Endometriosis","volume":"35","author":"Jackson C. B.","year":"1996","journal-title":"Contemporary Topics in Laboratory Animal Science"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1992.201.07.1077"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.etp.2007.06.001"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1177\/104063870902100426"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/vco.12456"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4612-4918-4_53"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.1330380243"},{"key":"e_1_2_9_29_1","first-page":"549","volume-title":"The Symposia of the National Zoological Park\u2014The Comparative Pathology of Zoo Animals","author":"McClure H. M.","year":"1980"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10024-003-8096-x"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.09-0511"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1066517"},{"issue":"5","key":"e_1_2_9_33_1","first-page":"512","article-title":"Splenic Vein Leiomyosarcoma: Case Report and Review of the Literature","volume":"15","author":"Patrono D.","year":"2014","journal-title":"Journal of the Pancreas [Electronic Resource]"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAP.0000000000000446"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-5-135"},{"key":"e_1_2_9_36_1","first-page":"879","article-title":"Leiomyosarcoma of the Spleen: A Rare Malignant Tumor","volume":"63","author":"Pletinchx N.","year":"2007","journal-title":"Tijdschrift Voor Geneeskunde"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001040170115"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semdp.2020.07.001"},{"key":"e_1_2_9_39_1","first-page":"533","article-title":"Neoplasms and Proliferative Lesions in 1065 Nonhuman Primate Necropsies","volume":"23","author":"Seibold H. R.","year":"1973","journal-title":"Laboratory Animal Science"},{"key":"e_1_2_9_40_1","first-page":"348","article-title":"Leiomyosarcoma of the Spleen","volume":"56","author":"Shapochnik M. B.","year":"2010","journal-title":"Voprosy Onkologii"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1177\/030098589403100105"},{"key":"e_1_2_9_42_1","first-page":"6","volume-title":"Atlas of Spontaneous and Chemically Induced Tumors in Nonhuman Primate","author":"Takayama S.","year":"2000"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1989.195.06.784"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0684.2007.00268.x"}],"container-title":["Veterinary Medicine and Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/vms3.70378","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/vms3.70378","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/vms3.70378","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T12:20:17Z","timestamp":1774268417000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/vms3.70378"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,24]]},"references-count":43,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1002\/vms3.70378"],"URL":"https:\/\/doi.org\/10.1002\/vms3.70378","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1002\/VMS3.70378\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.70378\/v3\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.70378\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.70378\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.70378\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.70378\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.70378\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.70378\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.70378\/v1\/review1","asserted-by":"object"}]},"ISSN":["2053-1095","2053-1095"],"issn-type":[{"value":"2053-1095","type":"print"},{"value":"2053-1095","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,24]]},"assertion":[{"value":"2024-07-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70378"}}