{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T17:59:07Z","timestamp":1780509547740,"version":"3.54.1"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T00:00:00Z","timestamp":1745798400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T00:00:00Z","timestamp":1745798400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp;amp; Sci"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Patent urachus is a common disease in newborn foals. However, despite its frequency, studies investigating symptoms, comorbidities, treatment and prognosis in a large number of affected foals have rarely been conducted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to describe the clinical symptoms, laboratory diagnostic findings and prognosis of foals with patent urachus.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>Data from 101 foals with a patent urachus from 2006 to 2017 were analysed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Patent urachus occurred at a frequency of 7.8% of all foals up to the 14th day of life during the study period. More colts (74.3%) than fillies (25.7%) were affected. In those with secondary urachal fistulae, patent urachus (91.1%) was significantly more diagnosed than persistent urachus (8.9%). Typical symptoms were a moist external umbilical environment (100%) and urine dripping from the external umbilical cord remnant during urination (75%). The average age at the time of diagnosis was 5.5\u00a0\u00b1\u00a03.2 days (median: 5 days, range: &lt;1\u201313 days). Umbilical resection was performed in 29.7% of foals, whereas 70.3% were treated conservatively. In total, 67.3% of affected foals were discharged from the clinic. Foals that underwent umbilical resection were discharged in 76.7%, and those that underwent conservative treatment in 63.4% of cases. No typical laboratory diagnostic findings related to patent urachus could be determined. However, an elevated lactate concentration on the day of admission was linked to significantly worsened prognosis (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.021). In 18.5% of the foals, which received surgery, a wound\u2010healing complication occurred at the abdominal suture. Further, 67% of the foals had one or more comorbidities. The presence of musculoskeletal disorders significantly worsened the survival prognosis (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.037). In total, 46 foals were monitored for at least 6 months (6 months to 10 years) after discharge from the clinic. At this point, 93.9% of the foals were alive, and none developed any further health complications with the umbilicus or abdominal sutures.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The primary result of this article is that patent urachus has a limited statistical influence on clinical parameters, laboratory values and prognosis. Comorbidities and\/or sequelae worsen survival prognosis. The prognosis in the first 6 months after discharge was very good.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/vms3.70379","type":"journal-article","created":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T13:44:43Z","timestamp":1745847883000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Patent Urachus and Associated Comorbidities in 101 Newborn Foals: A Retrospective Study"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-3335-0085","authenticated-orcid":false,"given":"Andr\u00e9","family":"Bernick","sequence":"first","affiliation":[{"name":"Veterinary Clinic for Reproductive Medicine and Neonatology Faculty of Veterinary Medicine Justus\u2010Liebig\u2010University Giessen  Giessen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2379-2613","authenticated-orcid":false,"given":"Judith","family":"Krohn","sequence":"additional","affiliation":[{"name":"Veterinary Clinic for Reproductive Medicine and Neonatology Faculty of Veterinary Medicine Justus\u2010Liebig\u2010University Giessen  Giessen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3313-4852","authenticated-orcid":false,"given":"Axel","family":"Wehrend","sequence":"additional","affiliation":[{"name":"Veterinary Clinic for Reproductive Medicine and Neonatology Faculty of Veterinary Medicine Justus\u2010Liebig\u2010University Giessen  Giessen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,28]]},"reference":[{"key":"e_1_2_11_2_1","first-page":"482","volume-title":"Urachal and Umbilical Disease. Equine Clinical Neonatology","author":"Adams R.","year":"1990"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1987.190.03.316"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1055\/a\u20101523\u20102711"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042\u20103306.2011.00509.x"},{"key":"e_1_2_11_6_1","first-page":"724","volume-title":"Handbuch Der Pferdepraxis","author":"Bostedt H.","year":"2017"},{"key":"e_1_2_11_7_1","unstructured":"B\u00e4umer G.1997. \u201cFohlenerkrankungen und\u2010verluste in den ersten Lebensabschnitten.\u201d Dissertation. Freie Universit\u00e4t Berlin Department of Veterinary Medicine."},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cveq.2021.11.004"},{"key":"e_1_2_11_9_1","first-page":"222","article-title":"Segmental Examination of the Neonatal Foal as a Standardised Clinical Procedure","volume":"91","author":"Ennen S.","year":"2010","journal-title":"Der Praktische Tierarzt"},{"key":"e_1_2_11_10_1","first-page":"94","article-title":"Ruptured Urachus in a Foal","volume":"77","author":"Ford J.","year":"1982","journal-title":"Veterinary Medicine, Small Animal Clinician"},{"key":"e_1_2_11_11_1","first-page":"176","article-title":"Nabelkomplikationen beim Fohlen und Ihre Behandlung","volume":"57","author":"Freytag K.","year":"1976","journal-title":"Der Praktische Tierarzt"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.15653\/TPG\u2010161102"},{"key":"e_1_2_11_13_1","first-page":"917","volume-title":"Equine Medicine and Surgery","author":"Hackett R. 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