{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T13:00:45Z","timestamp":1784552445591,"version":"3.55.0"},"reference-count":44,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T00:00:00Z","timestamp":1746489600000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp;amp; Sci"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Vector\u2010borne pathogens (VBPs) are frequently identified in domestic dogs, particularly in endemic areas or in individuals lacking protection from anti\u2010feeding products. Diagnostic procedures in veterinary clinics for symptomatic animals primarily include rapid serological assays; however, more definitive, albeit time\u2010intensive tests typically require well\u2010equipped laboratory facilities.<\/jats:p>\n                  <jats:p>\n                    A 5\u2010year\u2010old female mixed\u2010breed dog was presented to a veterinary clinic exhibiting neurological abnormalities, dyspnoea, lethargy and anorexia. Multiple ticks, predominantly of the genera\n                    <jats:italic>Rhipicephalus<\/jats:italic>\n                    and\n                    <jats:italic>Dermacentor<\/jats:italic>\n                    , were observed attached to the animal's integument. A blood smear examination revealed tachyzoites morphologically consistent with Toxoplasma spp. and intracellular morulae indicative of\n                    <jats:italic>Ehrlichia canis<\/jats:italic>\n                    infections. These findings were subsequently confirmed via polymerase chain reaction (PCR).\n                  <\/jats:p>\n                  <jats:p>This report documents a rare and fatal canine co\u2010infection of ehrlichiosis and toxoplasmosis, initially diagnosed through microscopic examination and serology, with definitive confirmation achieved through PCR analysis.<\/jats:p>","DOI":"10.1002\/vms3.70380","type":"journal-article","created":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T22:55:19Z","timestamp":1746572119000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["A Severe Clinical Case of\n                    <i>Ehrlichia canis<\/i>\n                    and\n                    <i>Toxoplasma gondii<\/i>\n                    in a Dog (With the First Morphological Detection of Tachyzoites in Peripheral Blood)"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-9692-5951","authenticated-orcid":false,"given":"Ioana","family":"Sandu","sequence":"first","affiliation":[{"name":"Department of Parasitology \u2010 Parasitic Diseases and Animal Biology University of Agronomic Sciences and Veterinary Medicine of Bucharest Bucharest Romania"},{"name":"Pet Stuff Veterinary Hospital Bucharest Bucharest Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6604-0839","authenticated-orcid":false,"given":"Georgiana","family":"Deak","sequence":"additional","affiliation":[{"name":"Department of Parasitology and Parasitic Diseases University of Agricultural Sciences and Veterinary Medicine of Cluj\u2010Napoca Cluj\u2010Napoca Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihai","family":"Turcitu","sequence":"additional","affiliation":[{"name":"Omnivet Impex SRL Bucharest Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter James","family":"O'Brien","sequence":"additional","affiliation":[{"name":"Department of Pathobiology University College Dublin Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viorica","family":"Mircean","sequence":"additional","affiliation":[{"name":"Department of Parasitology and Parasitic Diseases University of Agricultural Sciences and Veterinary Medicine of Cluj\u2010Napoca Cluj\u2010Napoca Romania"},{"name":"Dermatology Clinic University of Agricultural Sciences and Veterinary Medicine of Cluj\u2010Napoca Cluj\u2010Napoca Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,6]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939\u2010165x.2007.tb00190.x"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0102\u201009352012000100032"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2009.05.019"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751\u20100813.2006.tb13119.x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1999.215.08.1123"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens12010114"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/1040638721996685"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2016.03.021"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2019.00054"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1590\/0037\u20108682\u20100284\u20102014"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0195\u20105616(00)05006\u20103"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13028\u2010024\u201000734\u20100"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2020.109223"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2022.842595"},{"key":"e_1_2_10_16_1","volume-title":"Greene's Infectious Diseases of the Dog and Cat","author":"Greene C. 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