{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T04:21:08Z","timestamp":1778127668298,"version":"3.51.4"},"reference-count":76,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp;amp; Sci"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The objective of this study was to determine the effect of high fructose corn syrup (HFCS) and citric acid (CA) in broiler diets on performance, gut pH, immunity, antioxidant status and some blood parameters. A total of 120 Ross 308 chicks at the age of 0 days were divided into 4 groups with 3 subgroups of 10 chicks each: control (CON), 50\u00a0mg\/kg HFCS, 30\u00a0mg\/kg CA and 50\u00a0mg\/kg HFCS\u00a0+\u00a030\u00a0mg\/kg CA (HFCS\u00a0+\u00a0CA). It was determined that body weight gain (BWG) was highest in the CA group and was similar to the CON group, whereas it was lower in the HFCS\u00a0+\u00a0CA group than other groups (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0&lt;\u00a00.05). The feed conversion rates of the CA and the CON groups were similar and lower than the others (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0&lt;\u00a00.05). Carcass weights and ratios increased in the CA group (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0&lt;\u00a00.05). There were significant differences between the weights of liver and pancreas of groups (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0&lt;\u00a00.05). Serum high\u2010density lipoprotein (HDL)\u2010CHO and GLU levels increased in the HFCS\u00a0+\u00a0CA group (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0&lt;\u00a00.05). Serum total cholesterol (TCHO) level in the HFCS group was similar to the CON group and lower than the other groups (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0&lt;\u00a00.05). Serum tumour necrosis factor\u2010\u03b1 (TNF\u2010\u03b1) and interleukin\u20101\u03b2 (IL\u20101\u03b2) values were determined to be highest in the HFCS group and different from the CON group (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0&lt;\u00a00.05). It was observed that HFCS negatively affected performance, whereas CA positively affected. HFCS\u00a0+\u00a0CA increased serum TCHO and HDL\u2010CHO levels and CA led to an increasing trend in total antioxidant status (TAS) level. Although HFCS had a positive effect on TNF\u2010\u03b1 and IL\u20101\u03b2, similar of immunoglobulin G (IgG) and immunoglobulin M (IgM) levels between groups was observed.\n                  <\/jats:p>","DOI":"10.1002\/vms3.70436","type":"journal-article","created":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T12:18:16Z","timestamp":1748780296000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Effect of High Fructose Corn Syrup and Citric Acid in Broiler Diets on Performance, Gut pH, Immunity, Antioxidant Status and Some Blood Parameters"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6222-6986","authenticated-orcid":false,"given":"G\u00f6khan","family":"\u015een","sequence":"first","affiliation":[{"name":"Department of Animal Nutrition and Nutritional Diseases Faculty of Veterinary Medicine K\u0131r\u0131kkale University  Kirikkale Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Karapinar","sequence":"additional","affiliation":[{"name":"Department of Animal Nutrition and Nutritional Diseases Faculty of Veterinary Medicine K\u0131r\u0131kkale University  Kirikkale Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet Naci","family":"Oktay","sequence":"additional","affiliation":[{"name":"Department of Animal Breeding and Husbandry Faculty of Veterinary Medicine K\u0131r\u0131kkale University  Kirikkale Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miyase","family":"\u00c7inar","sequence":"additional","affiliation":[{"name":"Department of Biochemistry Faculty of Veterinary Medicine K\u0131r\u0131kkale University  Kirikkale Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet","family":"Ba\u015falan","sequence":"additional","affiliation":[{"name":"Department of Animal Nutrition and Nutritional Diseases Faculty of Veterinary Medicine K\u0131r\u0131kkale University  Kirikkale Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,6,1]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3923\/ijps.2008.215.222"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arabjc.2013.11.042"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1089\/jmf.2013.0065"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11010-009-0063-z"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.21608\/ejnf.2021.170317"},{"issue":"1","key":"e_1_2_9_7_1","first-page":"22","article-title":"Different Concentrations of High Fructose Corn Syrup in Broiler Diet Cause Different Effects on Selected Hematological Parameters","volume":"21","author":"Altu\u011f T.","year":"2024","journal-title":"Journal of Poultry Research"},{"key":"e_1_2_9_8_1","volume-title":"Ross Breeders Broiler Management Manual","author":"Anonymous","year":"2014"},{"key":"e_1_2_9_9_1","first-page":"729","article-title":"Effects of Citric Acid, Antibiotic Growth Promoter and Probiotics on Growth Performance of Broilers","volume":"578","author":"Asgar M. 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