{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T08:44:11Z","timestamp":1784709851583,"version":"3.55.0"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T00:00:00Z","timestamp":1752796800000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp;amp; Sci"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Fibrosing mediastinitis (FM) is a rare but serious condition characterized by excessive fibrous tissue proliferation in the mediastinum, often leading to compression of vital structures. Although considered benign, in people, clinical manifestations of FM can range from asymptomatic incidental findings on imaging studies to severe respiratory compromise and hemodynamic instability. While documented in people, FM has not yet been reported in dogs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>A 5\u2010year\u2010old male neutered Labrador Retriever presented with progressive respiratory distress, leading to pleural effusion and facial swelling. Thoracic radiographs revealed mediastinal mass\u2010like structures and pleural effusion. Computed tomography demonstrated a mediastinal mass\u2010like structure, enlarged tracheobronchial lymph nodes, multifocal narrowing of lobar bronchi and pulmonary veins and compression of the oesophagus and trachea. The dog was humanely euthanized due to poor response to empiric therapy and the owner's perception of suffering. A post\u2010mortem examination confirmed severe chronic mediastinal inflammation with fibrosis and vasculitis consistent with fibrosing mediastinitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This report presents a unique case of FM in a dog.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/vms3.70472","type":"journal-article","created":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T13:09:04Z","timestamp":1752844144000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Fibrosing Mediastinitis in a 5\u2010Year\u2010Old Labrador Retriever"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0348-9094","authenticated-orcid":false,"suffix":"Jr.","given":"Kyle L.","family":"Granger","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences College of Veterinary Medicine and Biomedical Sciences, Colorado State University  Fort Collins Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julien","family":"Guillaumin","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences College of Veterinary Medicine and Biomedical Sciences, Colorado State University  Fort Collins Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kurt","family":"Williams","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences and Oregon Veterinary Diagnostic Laboratory Carlson College of Veterinary Medicine, Oregon State University  Corvallis Oregon USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Shropshire","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences College of Veterinary Medicine and Biomedical Sciences, Colorado State University  Fort Collins Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Ohlendorf","sequence":"additional","affiliation":[{"name":"Department of Environmental and Radiological Health Sciences College of Veterinary Medicine and Biomedical Sciences, Colorado State University  Fort Collins Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5399-932X","authenticated-orcid":false,"given":"Kelly E.","family":"Hall","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences College of Veterinary Medicine and Biomedical Sciences, Colorado State University  Fort Collins Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,18]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmcr.2019.100987"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/1358863X19884130"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.21037\/cdt.2019.09.14"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy548"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.2019180143"},{"key":"e_1_2_10_7_1","volume-title":"StatPearls [Internet]","author":"Hanif M. O.","year":"2023"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-005-3161-x"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2006.09.034"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjrcr.20150274"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.4103\/atm.ATM_47_17"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.5737-20"},{"key":"e_1_2_10_13_1","first-page":"079","article-title":"Fibrosing Mediastinitis: A Review of Epidemiology, Diagnosis and Management","volume":"5","author":"Kuranga A.","year":"2018","journal-title":"International Journal of Respiratory and Pulmonary Medicine"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-198809000-00002"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.7196\/AJTCCM.2021.v27i2.064"},{"issue":"3","key":"e_1_2_10_16_1","article-title":"Fibrosing Mediastinitis Presenting With Superior Vena Cava Syndrome","volume":"14","author":"Park J. H.","year":"2022","journal-title":"Cureus"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0b013e318237c8e6"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/207056"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiographics.21.3.g01ma17737"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000001800"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13244-020-00909-z"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000010935"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacasi.2021.11.016"},{"issue":"3","key":"e_1_2_10_24_1","first-page":"263","article-title":"Hypoxic Hepatitis: A Review and Clinical Update","volume":"4","author":"Waseem N.","year":"2016","journal-title":"Journal of Clinical and Translational Hepatology"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201407-1258LE"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjresp-2016-000174"}],"container-title":["Veterinary Medicine and Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/vms3.70472","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/vms3.70472","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/vms3.70472","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T12:22:50Z","timestamp":1774268570000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/vms3.70472"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1002\/vms3.70472"],"URL":"https:\/\/doi.org\/10.1002\/vms3.70472","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1002\/VMS3.70472\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.70472\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.70472\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.70472\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.70472\/v1\/decision1","asserted-by":"object"}]},"ISSN":["2053-1095","2053-1095"],"issn-type":[{"value":"2053-1095","type":"print"},{"value":"2053-1095","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"2025-01-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70472"}}