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Single\u2010phase contrast\u2010enhanced computed tomography (CT) scan showed heterogeneous liver lobes with hyperattenuating parenchyma and multiple hypoattenuating lesions in the post\u2010contrast phase. No other primary neoplastic lesions were observed. Laparoscopic liver biopsy, histopathology and immunohistochemistry confirmed primary hepatic neuroendocrine carcinoma (PHNEC). Consequently, in cases where multiple hyperechoic nodules on ultrasound and hypoattenuating nodules on post\u2010contrast CT are observed in the liver, PHNEC should be considered as a differential diagnosis.<\/jats:p>","DOI":"10.1002\/vms3.70541","type":"journal-article","created":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T11:29:37Z","timestamp":1754047777000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Contrast\u2010Enhanced Computed Tomography Imaging Features of Primary Hepatic Neuroendocrine Carcinoma in a 4\u2010Year\u2010Old French Bulldog"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-4986-5019","authenticated-orcid":false,"given":"Hyeonji","family":"Sim","sequence":"first","affiliation":[{"name":"Department of Veterinary Medical Imaging, College of Veterinary Medicine Jeonbuk National University  Iksan Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9480-8163","authenticated-orcid":false,"given":"Sung\u2010Soo","family":"Kim","sequence":"additional","affiliation":[{"name":"VIP Animal Medical Center  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1270-3945","authenticated-orcid":false,"given":"Seoungyob","family":"Ahn","sequence":"additional","affiliation":[{"name":"VIP Animal Medical Center  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-9582-1158","authenticated-orcid":false,"given":"Amanda Jane","family":"Dennis","sequence":"additional","affiliation":[{"name":"IDEXX Laboratories, Inc.  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