{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T18:23:26Z","timestamp":1779906206465,"version":"3.53.1"},"reference-count":54,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T00:00:00Z","timestamp":1756080000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp;amp; Sci"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    To evaluate anticoccidial drug efficacy against\n                    <jats:italic>Eimeria tenella<\/jats:italic>\n                    in chicken, seven different field isolates were experimented with in battery cages with five commonly used anticoccidials as manufacturer doses, like amprolium (1\u00a0g\/L), maduramicin (5\u00a0ppm), sulphaclozine (2\u00a0g\/L), toltrazuril (25\u00a0mg\/L) and amprolium\u00a0+\u00a0sulphaquinoxaline (1\u00a0g\/L). One hundred twelve birds of the Ross strain were raised on a rice husk\u2013littered floor for the first 11 days with ad libitum water and anticoccidial\u2010free feed, facilitating a standard environment. On Day 12, the birds were divided into seven experimental groups with 16 birds each, and the respective anticoccidials were started for Groups I\u2013V and continued up to 7 days post\u2010infection. Each bird was infected with 7.5\u00a0\u00d7\u00a010\n                    <jats:sup>4<\/jats:sup>\n                    sporulated oocysts of\n                    <jats:italic>E. tenella<\/jats:italic>\n                    field isolates on Day 14. Global index (GI) was calculated by weight gain, feed conversion ratio (FCR), lesion score, oocyst index and mortality, followed by calculation of %GI\n                    <jats:sub>NNC<\/jats:sub>\n                    to determine the drug efficacy. Data obtained on various parameters were analysed using ANOVA, and the mean values were compared using the Duncan multiple range test through SPSS. The findings revealed that toltrazuril is the best among the experimental drugs, whereas amprolium and sulphaquinoxaline combination holds second place in terms of efficacy. However, the resistance of sulphaclozine was evident in all the isolates, whereas maduramicin showed limited efficacy to partial resistance against caecal coccidiosis. The study strongly recommends toltrazuril against chicken coccidiosis followed by amprolium but highly suggests avoiding long\u2010term use to maintain drug efficacy.\n                  <\/jats:p>","DOI":"10.1002\/vms3.70579","type":"journal-article","created":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T13:19:51Z","timestamp":1756127991000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Efficacy of Routinely Used Anticoccidials Against\n                    <i>Eimeria tenella<\/i>\n                    Field Isolates in Chicken: Bangladesh Perspective"],"prefix":"10.1002","volume":"11","author":[{"given":"Bimal Chandra","family":"Karmakar","sequence":"first","affiliation":[{"name":"Department of Parasitology Bangladesh Agricultural University  Mymensingh Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8130-8570","authenticated-orcid":false,"given":"Nusrat Nowrin","family":"Shohana","sequence":"additional","affiliation":[{"name":"Department of Parasitology Bangladesh Agricultural University  Mymensingh Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5462-7982","authenticated-orcid":false,"given":"Anita Rani","family":"Dey","sequence":"additional","affiliation":[{"name":"Department of Parasitology Bangladesh Agricultural University  Mymensingh Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7350-3093","authenticated-orcid":false,"family":"Anisuzzaman","sequence":"additional","affiliation":[{"name":"Department of Parasitology Bangladesh Agricultural University  Mymensingh Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2754-0571","authenticated-orcid":false,"given":"Sharmin Aqter","family":"Rony","sequence":"additional","affiliation":[{"name":"Department of Parasitology Bangladesh Agricultural University  Mymensingh Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shirin","family":"Akter","sequence":"additional","affiliation":[{"name":"Department of Parasitology Bangladesh Agricultural University  Mymensingh Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8040-2103","authenticated-orcid":false,"given":"Mohammad Zahangir","family":"Alam","sequence":"additional","affiliation":[{"name":"Department of Parasitology Bangladesh Agricultural University  Mymensingh Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8,25]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.3382\/japr.2008\u201000027"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.17140\/vmoj\u20108\u2010172"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/1541\u20104337.12763"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2025.e42773"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/vms3.799"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.5455\/jbau.20468"},{"issue":"2","key":"e_1_2_11_8_1","first-page":"234","article-title":"Evaluating the Resistance of Eimeria spp. Field Isolates to Anticoccidial Drugs Using Three Different Indices","volume":"8","author":"Arabkhazaeli F.","year":"2013","journal-title":"Irian Journal of Parasitology"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s43170\u2010021\u201000056\u20105"},{"key":"e_1_2_11_10_1","volume-title":"Livestock Economy at a Glance (2023\u201324)","author":"BBS","year":"2023"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/af\/vfac069"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2013.10.003"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13567\u2010020\u201000837\u20102"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2020.12.004"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.3382\/ps.2010\u201000931"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1586\/14760584.5.1.143"},{"issue":"1","key":"e_1_2_11_17_1","first-page":"150","article-title":"Efficacy of Toltrazuril Against Different Levels of Eimeria tenella Infection in Chicken","volume":"41","author":"Dhillon N. K.","year":"2004","journal-title":"Journal of Research, Punjab Agricultural University"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12917\u2010022\u201003369\u20103"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/s44280\u2010024\u201000039\u2010x"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.3382\/ps\/pev142"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00436\u2010020\u201007010\u2010w"},{"key":"e_1_2_11_22_1","first-page":"132","article-title":"Drug resistance in filed isolates of chicken coccidia from Punjab state","volume":"3","author":"Gill B. S.","year":"1979","journal-title":"Indian Journal of Parasitology"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004360000218"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.21276\/sjavs.2016.3.4.2"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/03079450802050705"},{"issue":"1","key":"e_1_2_11_26_1","first-page":"270","article-title":"Prevalence of Coccidiosis in Broiler Chicken","volume":"3","author":"Iqbal M. A.","year":"2018","journal-title":"International Journal of Animal and Fisheries Science"},{"key":"e_1_2_11_27_1","volume-title":"Poultry Diseases","author":"Jordan F. T. W.","year":"1998"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.3382\/ps.2010\u201001228"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2017.09.004"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0043933913000676"},{"key":"e_1_2_11_31_1","first-page":"45","article-title":"The prevalence of drug resistant cultures of coccidia","volume":"3","author":"Krylov V. F.","year":"1981","journal-title":"Veterinaria Moscow"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.3382\/ps\/pew499"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2009.04.020"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines10020215"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.3329\/jbau.v14i1.30597"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.3390\/foods11182738"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.19\u20100661"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.2307\/1591256"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2672.2012.05254.x"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijvsm.2018.06.003"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exppara.2020.107965"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.17420\/ap6701.315"},{"key":"e_1_2_11_43_1","volume-title":"The Impact of Antibiotic\u2010Free Production on Broiler Health","author":"Salois M.","year":"2017"},{"key":"e_1_2_11_44_1","first-page":"1","volume-title":"Guidelines on Techniques in Coccidiosis Research","author":"Shirley M. W.","year":"1995"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.3329\/bjm.v25i1.4860"},{"key":"e_1_2_11_46_1","first-page":"11","article-title":"Sulphonamide Resistance in Field Isolates of Chicken Coccidia in Bangladesh","volume":"17","author":"Siddiki A. Z.","year":"2000","journal-title":"Bangladesh Veterinarian"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2022.1031330"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0304\u20104017(96)01096\u20105"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psj.2023.102845"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2017.01245"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00436\u2010019\u201006338\u20102"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/3870902"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-4017(01)00512-X"},{"key":"e_1_2_11_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psj.2019.10.036"},{"key":"e_1_2_11_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsoil.2012.01.003"}],"container-title":["Veterinary Medicine and Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/vms3.70579","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T12:01:56Z","timestamp":1758715316000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/vms3.70579"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,25]]},"references-count":54,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["10.1002\/vms3.70579"],"URL":"https:\/\/doi.org\/10.1002\/vms3.70579","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1002\/VMS3.70579\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.70579\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.70579\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.70579\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.70579\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.70579\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.70579\/v2\/review1","asserted-by":"object"}]},"ISSN":["2053-1095","2053-1095"],"issn-type":[{"value":"2053-1095","type":"print"},{"value":"2053-1095","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,25]]},"assertion":[{"value":"2025-05-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70579"}}