{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T17:00:45Z","timestamp":1785085245218,"version":"3.55.0"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp; Sci"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:label\/>\n                    <jats:p>A total of 147 mares of different breeds (110 were sport or race horses, often very valuable) have been monitored over 5 years from 2012 to 2016. When at or near term, the mares were monitored in order to induce foaling, by checking the mammary development by palpation, analysing the colour and consistency of the precolostrum, estimating the calcium and antibodies concentrations in the precolostrum and by measuring the plasmatic progestagens concentration every day at 6 p.m.<\/jats:p>\n                    <jats:p>\n                      At the end of gestation, it has been observed that the progestagens rate levelled off (the top concentration varies from mare to mare: it can be as low as 35\u00a0ng\/mL or up to 260\u00a0ng\/mL) before falling sharply. Parturition was induced when the progestagens concentration fell of about 50% within 24 to 48\u00a0h. Induction was performed at 9 p.m. in 93 mares that followed the rule of the drop of progestagens (to respect the nycthemeral cycle) by a single IM oxytocin injection from 10 to 50 UI according to the weight of the mare (120 to 900\u00a0kg). Following the oxytocin injection, 90% (\n                      <jats:italic>n<\/jats:italic>\n                      = 84) of the foals were born within 20 to 50\u00a0min, 7.5% after 60\u00a0min (usually due to an excess of volume or dystocia), all alive and viable. Thirty to 60\u00a0min after birth, a manual delivery was performed for 71% (\n                      <jats:italic>n<\/jats:italic>\n                      = 66) of the mares. Among the 54 mares with spontaneous parturition (not induced because of insufficient proof of imminent birth), all foals were alive except for 2 twins that were found dead. A manual delivery was necessary for 17% (\n                      <jats:italic>n<\/jats:italic>\n                      = 9) of them. A 50% drop of the progestagens concentration is a good indication of the imminence of foaling: It is then safe to induce foaling, which usually results in a higher probability for a healthy foal and a reduced risk of genital lesions to the mare.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/vms3.70697","type":"journal-article","created":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T08:54:12Z","timestamp":1764233652000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Progestagens Monitoring in 147 Mares in Order to Induce Foaling With Oxytocin"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4885-6134","authenticated-orcid":false,"given":"Daniel","family":"Tainturier","sequence":"first","affiliation":[{"name":"Biotechnology and Pathology of Reproduction Nantes\u2010Atlantic National College of Veterinary Medicine, Food Science and Engineering  Oniris, Nantes Cedex France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benoit","family":"Tainturier","sequence":"additional","affiliation":[{"name":"French Military Service, 23\u00e8me Groupe V\u00e9t\u00e9rinaire, Garde R\u00e9publicaine  Paris Cedex France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandrine","family":"Michaud","sequence":"additional","affiliation":[{"name":"Biotechnology and Pathology of Reproduction Nantes\u2010Atlantic National College of Veterinary Medicine, Food Science and Engineering  Oniris, Nantes Cedex France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lamia","family":"Briand\u2010Amirat","sequence":"additional","affiliation":[{"name":"Biotechnology and Pathology of Reproduction Nantes\u2010Atlantic National College of Veterinary Medicine, Food Science and Engineering  Oniris, Nantes Cedex France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel","family":"Topie","sequence":"additional","affiliation":[{"name":"Biotechnology and Pathology of Reproduction Nantes\u2010Atlantic National College of Veterinary Medicine, Food Science and Engineering  Oniris, Nantes Cedex France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Moreno","sequence":"additional","affiliation":[{"name":"Biotechnology and Pathology of Reproduction Nantes\u2010Atlantic National College of Veterinary Medicine, Food Science and Engineering  Oniris, Nantes Cedex France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,27]]},"reference":[{"key":"e_1_2_11_2_1","first-page":"579","article-title":"Effectsof Placenta Pathology on Maternal Plasma Progestagen and Mammary Secretion Calcium Concentrations and on Neonatal Adrenocortical Function in the Horse","volume":"44","author":"Allen W. R.","year":"1991","journal-title":"Journal of Reproduction and Fertility"},{"key":"e_1_2_11_3_1","first-page":"545","article-title":"Observations on the Time of Foaling in Thoroughbred Mares in Australia","volume":"23","author":"Bain A. M.","year":"1975","journal-title":"Journal of Reproduction and Fertility"},{"key":"e_1_2_11_4_1","first-page":"662","article-title":"L'accouchement Provoqu\u00e9 par L'hormone Post\u2010hypophysaire cheZ la jument","volume":"107","author":"Berthelon M.","year":"1956","journal-title":"Revue de Medecine Veterinaire"},{"key":"e_1_2_11_5_1","first-page":"55","article-title":"Therapy for Retained Placenta in the Mare","volume":"88","author":"Blanchard T. L.","year":"1993","journal-title":"Equine Practice"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516400777032147"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1985.tb02044.x"},{"key":"e_1_2_11_8_1","first-page":"837","article-title":"The Use of Microdoses of Oxytocin in Mares to Unduce Parturition","volume":"58","author":"Chavatte\u2010Palmer P.","year":"2001","journal-title":"Theriogenology"},{"key":"e_1_2_11_9_1","first-page":"2268","volume-title":"Equine Reproduction","author":"Chritensen B. W.","year":"2011"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0531.1995.tb00141.x"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3292.2003.tb00223.x"},{"key":"e_1_2_11_12_1","first-page":"266","article-title":"Endocrinologie: Comprendre le Dialogue Entre Jument Et F\u0153tus Lors De la Parturition","volume":"7","author":"Hess\u2010Dudan F. E.","year":"2006","journal-title":"Le Nouveau Praticien V\u00e9t\u00e9rinaire \u00e9quine"},{"key":"e_1_2_11_13_1","first-page":"641","article-title":"Induction of Parturition in Mares","volume":"23","author":"Hillman R. B..","year":"1975","journal-title":"Journal of Reproduction and Fertility Supplement"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.1982.43.10.1752"},{"key":"e_1_2_11_15_1","first-page":"517","article-title":"Progestagens in the Mares, Fetus and Newborn Foal","volume":"44","author":"Holtan D. W.","year":"1991","journal-title":"Journal of Reproduction and Fertility"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.2527\/jas1951.104789x"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1984.tb01922.x"},{"key":"e_1_2_11_18_1","first-page":"2262","volume-title":"Equine Reproduction","author":"Macpherson M. L.","year":"2011"},{"key":"e_1_2_11_19_1","article-title":"Three Methods of Oxytocin\u2010Induced Parturition and Their Effects on Foals","author":"Macpherson M. L.","year":"1997","journal-title":"Journal of the American Medical Informatics Association"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.2011.00476.x"},{"key":"e_1_2_11_21_1","first-page":"165","article-title":"Induction of Parturition in the Healthy Mare","author":"Ousey J.","year":"2003","journal-title":"Equine Veterinary Education"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1984.tb01923.x"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1984.tb01924.x"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1980.tb02316.x"},{"key":"e_1_2_11_25_1","article-title":"The R\u00f4le of the Fetal Gonads and Placenta in Steroid Reproduction, Maintenance of Pregnancy and Parturition in the Mare","volume":"27","author":"Pashen R. U.","year":"1979","journal-title":"Journal of Reproduction and Fertility"},{"key":"e_1_2_11_26_1","first-page":"555","article-title":"Changes in Mammary Development and Composition of Secretion During Late Pregnancy in the Mare","volume":"8","author":"Peaker M.","year":"1979","journal-title":"Journal of Reproduction and Fertility Supplement"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/eve.13046"},{"key":"e_1_2_11_28_1","first-page":"145","article-title":"The Induction of Labor in Mares as a Routine Breeding Farm Procedure","volume":"23","author":"Purvis A. D..","year":"1977","journal-title":"Proceeding of the 23 Rd Annual Conference of the American Association of Equine Practitioners"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1080\/00480169.2016.1244021"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.99.2.26"},{"key":"e_1_2_11_31_1","first-page":"463","article-title":"L'accouchement Provoqu\u00e9 Chez la Jument par les Prostaglandines","volume":"136","author":"Tainturier D..","year":"1985","journal-title":"Revue de Medecine Veterinaire"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0531.2007.00940.x"}],"container-title":["Veterinary Medicine and Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/vms3.70697","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/vms3.70697","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/vms3.70697","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T16:43:00Z","timestamp":1785084180000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/vms3.70697"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,27]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1002\/vms3.70697"],"URL":"https:\/\/doi.org\/10.1002\/vms3.70697","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1002\/VMS3.70697\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.70697\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.70697\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.70697\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/VMS3.70697\/v2\/response1","asserted-by":"object"}]},"ISSN":["2053-1095","2053-1095"],"issn-type":[{"value":"2053-1095","type":"print"},{"value":"2053-1095","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,27]]},"assertion":[{"value":"2025-03-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70697"}}