{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T09:49:14Z","timestamp":1791798554381,"version":"4.3.4"},"reference-count":86,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T00:00:00Z","timestamp":1769731200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T00:00:00Z","timestamp":1769731200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100007831","name":"University of Tabriz","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007831","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp;amp; Sci"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The bioavailability of trace minerals (TM) in a diet is important for improving reproductive performance and fertility parameters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study evaluated the effects of replacing inorganic trace minerals (ITM) with organic trace minerals (OTM), formulated using advanced chelate technology, on the reproductive performance and blood attributes of ewes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Forty ewes were subjected to a five\u2010week intervention in four dietary groups (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a010): (1) OTM: flushed with organic trace minerals (Bonzaplex\u20107); (2) ITM: flushed with inorganic trace minerals; (3) NTM: flushed without adding trace minerals; and (4) CON: grazed only on pasture. Oestrus synchronization was performed based on two doses of 75\u00a0\u00b5g cloprostenol with 12\u00a0days interval\u00a0+\u00a0400\u00a0IU eCG injection. The number of follicles and pregnancy were determined by ultrasound. Blood samples were collected at predetermined time points during the experimental period (Days 0, 11, 14 and 34).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      OTM (80%) and ITM (90%) groups exhibited higher first\u2010cycle pregnancy rates, as well as improved lambing and twinning rates. OTM demonstrated the greatest efficiency across all reproductive indices. However, follicle number was not affected by the treatments. Also, T3 and T4, as well as triglycerides, were higher in the OTM group as compared with other groups (\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      &lt;\u00a00.05). Serum estradiol, progesterone and antioxidant enzymes were not affected by treatments (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&gt;\u00a00.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Overall, supplementing advanced chelate technology\u2010based OTM in the flushing diet improved the reproductive performance of ewes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/vms3.70763","type":"journal-article","created":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T14:31:57Z","timestamp":1769783517000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Impact of Feeding Organic Trace Minerals Using Advanced Chelate Technology on Reproductive Efficiency and Blood Parameters in Ghezel Ewes"],"prefix":"10.1002","volume":"12","author":[{"given":"Sedigheh","family":"Vatankhah","sequence":"first","affiliation":[{"name":"Department of Animal Science Faculty of Agriculture University of Tabriz, Tabriz  East Azarbaijan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marziyeh","family":"Ebrahimi","sequence":"additional","affiliation":[{"name":"Department of Animal Science Faculty of Agriculture University of Tabriz, Tabriz  East Azarbaijan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gholamali","family":"Moghaddam","sequence":"additional","affiliation":[{"name":"Department of Animal Science Faculty of Agriculture University of Tabriz, Tabriz  East Azarbaijan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davoud","family":"Kianifard","sequence":"additional","affiliation":[{"name":"Department of Basic Sciences Faculty of Veterinary Medicine University of Tabriz, Tabriz  East Azarbaijan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akbar","family":"Taghizadeh","sequence":"additional","affiliation":[{"name":"Department of Animal Science Faculty of Agriculture University of Tabriz, Tabriz  East Azarbaijan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reza","family":"Asadpour","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Faculty of Veterinary Medicine University of Tabriz, Tabriz  East Azarbaijan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9413-2295","authenticated-orcid":false,"given":"Mohammad Hassan","family":"Nazaran","sequence":"additional","affiliation":[{"name":"Department of Research and Development Sodour Ahrar Shargh Company  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,30]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/8530961"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.9775\/kvfd.2009.1131"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1530\/rep.1.00389"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2005.06.018"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2010.06.001"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12011\u2010018\u20101448\u20101"},{"key":"e_1_2_11_8_1","first-page":"183","article-title":"Effects of Feeding Different Trace Mineral Sources on Performance and Health of Afshari Ewes and Lambs","volume":"51","author":"Amanlou H.","year":"2020","journal-title":"Iranian Journal of Applied Animal Science"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2007.12.022"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.5194\/aab\u201047\u2010265\u20102004"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani12040510"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1042\/cs0980593"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani11061730"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani12151981"},{"key":"e_1_2_11_15_1","volume-title":"Book of Clinical Practical Chemistry","author":"Cannan R. 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