{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T09:49:30Z","timestamp":1791798570460,"version":"4.3.4"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T00:00:00Z","timestamp":1770163200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T00:00:00Z","timestamp":1770163200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp;amp; Sci"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Dental health in cattle affects food intake and productivity. However, dental diseases are often overlooked. Tooth erosion, pigment deposition and periodontal diseases are common. Periodontal structures, especially extracellular matrix components such as proteoglycans, play an important role in tissue homeostasis and inflammatory processes. Analysis of GCF can provide important information in understanding the pathogenesis of periodontal diseases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>This study aimed to identify the primary dental and gingival lesions affecting dairy cattle and evaluate their impact on periodontal health parameters. In addition, it sought to determine the presence of proteoglycans, specifically decorin, in GCF samples from cattle with dental inflammation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and method<\/jats:title>\n                    <jats:p>A total of 100 randomly selected dairy cattle were examined and oral and periodontal lesions were recorded. Clinical evaluation data (PI, GI, PPD and BPI) were evaluated. In the second part, comparative decorin levels of GCF samples from 10 healthy and 10 diseased cattle were measured.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>GI values were 3% Grade 0, 22% Grade 1, 37% Grade 2 and 38% Grade 3. PI values were 25% Grade 1, 35% Grade 2 and 40% Grade 3. The mean approximate value of PPD was 4.96\u00a0mm (max: 8, min: 1). BPI was not seen in 79% of the cases. The mean value of the control group was calculated as 38.3\u00a0\u00b1\u00a02.27\u00a0ng\/mL, while that of the case group was 26.59\u00a0\u00b1\u00a01.42\u00a0ng\/mL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Routine periodontal assessment in cattle can help maintain dental health and improve animal welfare. Despite their disadvantages, biomarkers offer promising potential for developing non\u2010invasive diagnostic methods.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/vms3.70821","type":"journal-article","created":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T07:57:46Z","timestamp":1770278266000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Determination of Dental Lesions in Dairy Cattle and Immunochemical Detection of the Biomarker Decorin in Gingival Crevicular Fluid of Dairy Cattle"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6789-8474","authenticated-orcid":false,"given":"Nihan","family":"AVCI","sequence":"first","affiliation":[{"name":"Faculty of Veterinary Medicine Department of Surgery Aksaray University  Aksaray T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,4]]},"reference":[{"issue":"4","key":"e_1_2_12_2_1","first-page":"229","article-title":"Problems and Proposals for Recording Gingivitis and Plaque","volume":"25","author":"Ainamo J.","year":"1975","journal-title":"International Dental Journal"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-5193(74)90103-9"},{"issue":"5","key":"e_1_2_12_4_1","first-page":"126","article-title":"Oral Fluid\u2010Based Biomarkers in Periodontal Disease\u2014Part 2. Gingival Crevicular Fluid","volume":"6","author":"AlRowis R.","year":"2014","journal-title":"Journal of International Oral Health"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/08987564211065129"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.936021"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani11071870"},{"issue":"1","key":"e_1_2_12_8_1","first-page":"1","article-title":"Cheek Teeth Apical Infection in Cattle: Diagnosis, Surgical Extraction, and Prognosis","volume":"26","author":"Constant C.","year":"2019","journal-title":"Veterinary Surgery"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.S0022\u20100302(04)73142\u20102"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/089875641202900314"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.103266"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.3780197"},{"issue":"1","key":"e_1_2_12_13_1","first-page":"117","article-title":"Alteration of Decorin Synthesis in Gingival Fibroblasts Induced by Interleukin\u20101\u03b2","volume":"1","author":"Kawamoto A.","year":"2004","journal-title":"Journal of Oral Tissue Engineering"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12194"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016356309011240"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1096\/fasebj.10.5.8621059"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2012.04.029"},{"issue":"2","key":"e_1_2_12_18_1","first-page":"256","article-title":"Pregnancy Adaptation and Prenatal Attachment Levels of Pregnant Women at Threat of Pre\u2010Term Birth and Those Not at Threat of Pre\u2010Term Birth","volume":"4","author":"Ozmen T.","year":"2023","journal-title":"Journal of Selcuk Health"},{"issue":"11","key":"e_1_2_12_19_1","first-page":"409","article-title":"Postmortem Examination of Bovine Dental Disorders","volume":"71","author":"Probst J. 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