{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T09:49:22Z","timestamp":1791798562374,"version":"4.3.4"},"reference-count":49,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:00:00Z","timestamp":1773014400000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp;amp; Sci"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Enteropathogenic\n                      <jats:italic>Escherichia coli<\/jats:italic>\n                      (EPEC) contamination of retail chicken meat is a significant cause of public health concern among susceptible groups like children, the elderly, and immunocompromised individuals.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The current research was conducted to identify the prevalence, genotypic pattern and drug resistance of multidrug\u2010resistant EPEC (MDR\u2010EPEC) in chicken meat during January to June 2024 in Kuliarchar and Bhairab upazilas, Bangladesh.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A total of 140 retail chicken meat samples were collected from Kuliarchar and Bhairab upazilas between January and June 2024. The isolates were confirmed by primary culture, biochemical reactions, and molecular confirmation by PCR employing\n                      <jats:italic>phoA<\/jats:italic>\n                      and\n                      <jats:italic>eaeA<\/jats:italic>\n                      genes. Antimicrobial susceptibility testing was conducted using disk diffusion as per the CLSI 2020 standard.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Overall prevalence of\n                      <jats:italic>E. coli<\/jats:italic>\n                      was 68.6% (95% CI: 60.2\u201376.2) and was found to be higher in Bhairab (81.6%) compared to Kuliarchar (47.2%). 8.6% of these were found to be EPEC. All the retrieved EPEC were resistant to ampicillin, and 91.7% were resistant to ceftazidime and gentamicin. Amoxicillin\u2013clavulanic acid and ciprofloxacin were the most effective antimicrobials. All EPEC isolates (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a012) exhibited resistance to three or more antimicrobial classes and were therefore classified as multidrug\u2010resistant. Genotypic analysis showed high prevalence of\n                      <jats:italic>bla<\/jats:italic>\n                      <jats:sub>TEM\u20101, 2<\/jats:sub>\n                      (91.7%),\n                      <jats:italic>bla<\/jats:italic>\n                      <jats:sub>SHV\u20101<\/jats:sub>\n                      (66.7%),\n                      <jats:italic>bla<\/jats:italic>\n                      <jats:sub>OXA\u20101, 4 &amp; 30<\/jats:sub>\n                      (33.3%), with\n                      <jats:italic>aac(3)\u2010iv<\/jats:italic>\n                      (83.3%),\n                      <jats:italic>sul1<\/jats:italic>\n                      (41.7%) and\n                      <jats:italic>tet(A)<\/jats:italic>\n                      (25.0%), indicating widespread \u03b2\u2010lactam and gentamicin resistance in EPEC. The multiple antibiotic resistance (MAR) index was 0.40\u20130.50, which indicated exposure to high antibiotic pressure.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The findings justify stricter food safety controls, effective use of antibiotics and proper hygiene to provide for the avoidance of the dissemination of MDR\u2010EPEC through infected chicken meat and public health safety.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/vms3.70876","type":"journal-article","created":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T14:39:35Z","timestamp":1773067175000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Molecular Screening and Antibiogram Profile of Multidrug\u2010Resistant Enteropathogenic\n                    <i>Escherichia coli<\/i>\n                    Isolated From Retail Chicken Meat"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-7526-7685","authenticated-orcid":false,"given":"Sakibul Haque","family":"Zilon","sequence":"first","affiliation":[{"name":"Department of Pathology Sylhet Agricultural University  Sylhet Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9785-2549","authenticated-orcid":false,"given":"Hemayet","family":"Hossain","sequence":"additional","affiliation":[{"name":"Department of Veterinary Science and Animal Husbandry Teesta University  Rangpur Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0210-6581","authenticated-orcid":false,"given":"Md. Shahidur Rahman","family":"Chowdhury","sequence":"additional","affiliation":[{"name":"Department of Medicine Sylhet Agricultural University  Sylhet Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-1186-973X","authenticated-orcid":false,"given":"Sojib","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Pathology Sylhet Agricultural University  Sylhet Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-4605-5744","authenticated-orcid":false,"given":"Asikur","family":"Rahman","sequence":"additional","affiliation":[{"name":"Department of Medicine Sylhet Agricultural University  Sylhet Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9390-4401","authenticated-orcid":false,"given":"Sumaya Shargin","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Medicine Sylhet Agricultural University  Sylhet Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4118-0784","authenticated-orcid":false,"given":"Margia","family":"Akter","sequence":"additional","affiliation":[{"name":"Department of Pathology Sylhet Agricultural University  Sylhet Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4407-168X","authenticated-orcid":false,"given":"Bashudeb","family":"Paul","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Histology Sylhet Agricultural University  Sylhet Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1402-3660","authenticated-orcid":false,"given":"Mohammad Ali","family":"Zinnah","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Public Health Gazipur Agricultural University  Gazipur Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9435-113X","authenticated-orcid":false,"given":"Monira","family":"Noor","sequence":"additional","affiliation":[{"name":"Department of Pathology Sylhet Agricultural University  Sylhet Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2062-8471","authenticated-orcid":false,"given":"Md. 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