{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T15:47:15Z","timestamp":1791906435535,"version":"4.3.4"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T00:00:00Z","timestamp":1774569600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T00:00:00Z","timestamp":1774569600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp;amp; Sci"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Bovine respiratory disease (BRD) is a leading cause of morbidity and mortality in the cattle industry worldwide, resulting in substantial economic losses.\n                    <jats:italic>Trueperella pyogenes<\/jats:italic>\n                    has been recognized as an opportunistic pathogen; however, its role as a primary aetiologic agent of BRD remains poorly defined. Four Korean native calves developed respiratory signs, including coughing, nasal discharge and pneumonia, and died within 1\u20132 days after onset. Postmortem examination revealed characteristic gross pulmonary lesions. PCR was performed to detect common BRD pathogens and antimicrobial resistance (AMR) genes.\n                    <jats:italic>T. pyogenes<\/jats:italic>\n                    was identified in the lungs of all calves examined. Three calves were infected solely with\n                    <jats:italic>T. pyogenes<\/jats:italic>\n                    , whereas one calf was co\u2010infected with three pathogens (\n                    <jats:italic>Histophilus somni<\/jats:italic>\n                    ,\n                    <jats:italic>Mycoplasma dispar<\/jats:italic>\n                    and\n                    <jats:italic>Pasteurella multocida<\/jats:italic>\n                    ) as well as\n                    <jats:italic>T. pyogenes<\/jats:italic>\n                    . AMR genes, predominantly the macrolide resistance genes\n                    <jats:italic>ermX<\/jats:italic>\n                    and\n                    <jats:italic>ermB<\/jats:italic>\n                    , were detected in three calves. To the best of our knowledge, this is the first report of\n                    <jats:italic>T. pyogenes<\/jats:italic>\n                    \u2010associated pneumonia and the characterization of AMR genes in Korean native calves. This case indicates that\n                    <jats:italic>T. pyogenes<\/jats:italic>\n                    can act as a major pathogen responsible for BRD in calves. These findings highlight the pathogenic potential of\n                    <jats:italic>T. pyogenes<\/jats:italic>\n                    and the need for targeted therapeutic approaches to support prudent antimicrobial use in cattle.\n                  <\/jats:p>","DOI":"10.1002\/vms3.70913","type":"journal-article","created":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T05:50:57Z","timestamp":1774677057000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["<i>Trueperella pyogenes<\/i>\n                    \u2013Associated Acute Pneumonia in Korean Native Calves"],"prefix":"10.1002","volume":"12","author":[{"given":"Min\u2010Jeong","family":"Ji","sequence":"first","affiliation":[{"name":"Department of Animal Science and Biotechnology, College of Ecology and Environmental Science Kyungpook National University  Sangju Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youngjun","family":"Kim","sequence":"additional","affiliation":[{"name":"Hanwoo (Korean Indigenous Cattle) Genetic Improvement Center Nonghyup Agribusiness Group Inc.  Seosan Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byoung\u2010Soo","family":"Kim","sequence":"additional","affiliation":[{"name":"Yeongkwang Veterinary Clinic  Yeonggwang Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jongho","family":"Kim","sequence":"additional","affiliation":[{"name":"Animal Disease Diagnostic Division Animal and Plant Quarantine Agency  Gimcheon Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2271-5360","authenticated-orcid":false,"given":"Kyoung\u2010Seong","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Animal Science and Biotechnology, College of Ecology and Environmental Science Kyungpook National University  Sangju Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,27]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics13040322"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.7589\/2016-02-035"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetimm.2007.01.007"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2017.00207"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2022.109571"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.14-0657"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2025.1605045"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11250-019-01916-z"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens10010064"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.17221\/119\/2020-VETMED"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/104063870902100407"},{"issue":"2016","key":"e_1_2_11_13_1","article-title":"Multifocal Pulmonary Abscesses due to Trueperella pyogenes in Sheep","volume":"10","author":"Hariharan H.","year":"2016","journal-title":"International Journal of Veterinary Medicine: Research & Reports"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.7589\/0090-3558-43.2.189"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2024.1362352"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02485-13"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics10040380"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1128\/msphere.00239-23"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13567-025-01468-1"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.17555\/jvc.2019.08.36.4.185"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1128\/iai.00273-23"},{"key":"e_1_2_11_22_1","volume-title":"Veterinary Medicine: A Textbook of the Diseases of Cattle, Horses, Sheep, Pigs and Goats","author":"Radostits O. 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