{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T15:47:02Z","timestamp":1791906422830,"version":"4.3.4"},"reference-count":12,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:00:00Z","timestamp":1777507200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:00:00Z","timestamp":1777507200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp;amp; Sci"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>This report presents a case of congenital hypothyroidism in a 3\u2010year\u2010old female Persian cat, a condition that is seldom encountered in feline patients. The cat was presented with chronic renal failure and stunted growth, exhibiting a unique combination of symptoms, including dwarfism, an abnormal skull shape and open growth plates. A complete blood count (CBC) identified moderate anaemia, while the biochemical analysis showed elevated serum creatinine levels and blood urea nitrogen (BUN) levels.<\/jats:p>\n                  <jats:p>Low serum total thyroxine (TT4) concentrations, both before and after the administration of thyroid\u2010stimulating hormone (TSH), confirmed the presumptive diagnosis of congenital hypothyroidism. Following this, levothyroxine supplementation was initiated. After 1 week of therapy, the cat displayed decreased creatinine levels and increased activity.<\/jats:p>\n                  <jats:p>This case highlights that feline hypothyroidism, although rare, should be considered a differential diagnosis in similar cases.<\/jats:p>","DOI":"10.1002\/vms3.70949","type":"journal-article","created":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T10:23:21Z","timestamp":1777544601000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Case of Congenital Hypothyroidism in Cats: Diagnostic Challenges and Therapeutic Outcomes"],"prefix":"10.1002","volume":"12","author":[{"given":"Morteza Ezati","family":"Kakalar","sequence":"first","affiliation":[{"name":"Department of Small Animal Internal Medicine, Faculty of Veterinary Medicine University of Tehran  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farkhondeh Fahim","family":"Dezhban","sequence":"additional","affiliation":[{"name":"Department of Radiology and Surgery, Faculty of Veterinary Medicine University of Tehran  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1017-1067","authenticated-orcid":false,"given":"Amin","family":"Zamani","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine Karaj Branch, Islamic Azad University  Karaj Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sina Sabour","family":"Razlighi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Faculty of Veterinary Medicine University of Garmsar  Garmsar Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,30]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"56","volume-title":"Hayvan Besleme ve Beslenme Hastal\u0131klar\u0131","author":"Altiner A.","year":"2024"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/00480169.2011.567964"},{"key":"e_1_2_10_4_1","unstructured":"Cornell University College of Veterinary Medicine. n.d. \u201cChemistry Reference Intervals\u2014Cobas.\u201d Accessed June 11 2025.https:\/\/www.vet.cornell.edu\/animal\u2010health\u2010diagnostic\u2010center\/laboratories\/clinical\u2010pathology\/reference\u2010intervals\/chemistry\u2010cobas."},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.22456\/1679-9216.104148"},{"key":"e_1_2_10_6_1","first-page":"286","volume-title":"Ettinger's Textbook of Veterinary Internal Medicine","author":"Ettinger S. 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