{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T12:19:32Z","timestamp":1787919572626,"version":"build-2784847793"},"reference-count":100,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:00:00Z","timestamp":1779926400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:00:00Z","timestamp":1779926400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp; Sci"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Brucellosis remains an important zoonotic disease in Bangladesh, yet evidence on its prevalence across human and animal hosts is fragmented and heterogeneous.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      This study aims to synthesize evidence on\n                      <jats:italic>Brucella<\/jats:italic>\n                      detection across human and animal hosts in Bangladesh and to evaluate associated study\u2010level factors and temporal patterns.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The data were extracted from eligible studies published between 2000 and 2024 following a systematic review framework. Pooled prevalence was estimated using a random\u2010effects meta\u2010analysis. Heterogeneity was assessed using Cochran's\n                      <jats:italic>Q<\/jats:italic>\n                      and\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      statistics. Subgroup meta\u2010analyses and univariable meta\u2010regression were conducted to examine variation by host species, diagnostic method, and study\u2010level factors. Forecasting was performed using ARIMA models on annual study\u2010reported\n                      <jats:italic>Brucella<\/jats:italic>\n                      detection, with model performance evaluated using AIC, MAE, and RMSE.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The pooled\n                      <jats:italic>Brucella<\/jats:italic>\n                      detection across hosts was 3.75% (95% CI: 3.07\u20134.56), with substantial heterogeneity (\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      = 89.5%). Detection was the highest in dogs (7.49%) and the lowest in horses (1.78%)). Among evaluated variables, abortion history was the only study\u2010level factorsignificantly associated with higher\n                      <jats:italic>Brucella<\/jats:italic>\n                      positivity, with aborted animals showing approximately 10 times higher odds of detection compared to non\u2010aborted animals (OR = 10.09, 95% CI: 4.64\u201321.93,\n                      <jats:italic>p<\/jats:italic>\n                      &lt;0.001). Temporal patterns suggested a decreasing trend in goats and an increasing trend in cattle; however, these likely reflect variation in study design, diagnostics, and coverage rather than true epidemiological change.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Brucella<\/jats:italic>\n                      exposure and detection persist across multiple host species in Bangladesh, with variation largely driven by methodological and host\u2010related differences. These findings underscore the need for standardized diagnostic and reporting approaches and support integrated One Health surveillance to improve interpretation and control strategies in Bangladesh.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/vms3.71005","type":"journal-article","created":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T13:07:44Z","timestamp":1779973664000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence, Associated Factors, and Temporal Trends of\n                    <i>Brucella<\/i>\n                    Detection Across Human and Animal Hosts in Bangladesh: A 25\u2010Year Meta\u2010Analysis"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-3565-6968","authenticated-orcid":false,"given":"Radwan","family":"Raquib","sequence":"first","affiliation":[{"name":"Faculty of Veterinary Animal and Biomedical Sciences Sylhet Agricultural University  Sylhet Bangladesh"},{"name":"Department of Parasitology Sylhet Agricultural University  Sylhet Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farhaj Ahammed","family":"Arnob","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Animal and Biomedical Sciences Sylhet Agricultural University  Sylhet Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-7782-4550","authenticated-orcid":false,"given":"Riyadh","family":"Hossain","sequence":"additional","affiliation":[{"name":"Department of Statistics Noakhali Science and Technology University  Noakhali Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahsan","family":"Raquib","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Public Health Sylhet Agricultural University  Sylhet Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-7385-7952","authenticated-orcid":false,"given":"Tajul Islam","family":"Mamun","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Animal and Biomedical Sciences Sylhet Agricultural University  Sylhet Bangladesh"},{"name":"Department of Epidemiology and Public Health Sylhet Agricultural University  Sylhet Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,28]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.4178\/epih.e2016042"},{"issue":"2","key":"e_1_2_10_3_1","first-page":"121","article-title":"A Sero\u2010Surveillance of Brucella spp. Antibodies and Individual Risk Factors of Infection in Cattle of Bangladesh","volume":"33","author":"Ahasan M. 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