{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T13:16:30Z","timestamp":1787922990547,"version":"build-2784847793"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:00:00Z","timestamp":1782777600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:00:00Z","timestamp":1782777600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp; Sci"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the clinical feasibility and anaesthetic efficacy of a combined Bier block and brachial plexus block administered with xylazine sedation (seda\u2010block) for metacarpal and radioulnar osteosynthesis in neonatal calves, and to compare this technique with conventional xylazine\u2013ketamine anaesthesia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Prospective controlled pilot study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Fourteen client\u2010owned neonatal calves undergoing unilateral forelimb osteosynthesis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Calves were randomly allocated to two groups: seda\u2010block (SB;\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a07), receiving intravenous xylazine combined with brachial plexus block and intravenous regional anaesthesia, and xylazine\u2013ketamine (XK;\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a07), receiving intravenous xylazine followed by ketamine. Sedation quality, desensitization, surgeon satisfaction, xylazine consumption and need for supplemental dosing were evaluated intraoperatively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Sedation scores, desensitization scores and surgeon satisfaction did not differ significantly between groups. Total xylazine consumption and surgery duration were comparable. Repeated xylazine administration was required in both groups to maintain immobility; however, adequate surgical conditions were achieved without conversion to general anaesthesia in the seda\u2010block group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion and Clinical Relevance<\/jats:title>\n                    <jats:p>The combined use of Bier block and brachial plexus block with xylazine sedation may provide clinically acceptable surgical conditions under the specific conditions of this study, and could represent a practical alternative to general anaesthesia in selected neonatal calves.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/vms3.71069","type":"journal-article","created":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T08:48:36Z","timestamp":1782809316000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of Seda\u2010Block and Xylazine\u2013Ketamine Anaesthesia for Metacarpal and Radioulnar Osteosynthesis in Calves"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8855-8847","authenticated-orcid":false,"given":"M\u00fcmin G\u00f6khan","family":"\u015eenocak","sequence":"first","affiliation":[{"name":"Department of Surgery Faculty of Veterinary Medicine Atat\u00fcrk University  Erzurum Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c7a\u011flar","family":"\u00d6zkalip\u00e7i","sequence":"additional","affiliation":[{"name":"Department of Surgery Faculty of Veterinary Medicine Atat\u00fcrk University  Erzurum Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taner","family":"Arslan","sequence":"additional","affiliation":[{"name":"Department of Surgery Faculty of Veterinary Medicine Atat\u00fcrk University  Erzurum 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