{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T12:54:45Z","timestamp":1791204885365,"version":"4.1.0"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:00:00Z","timestamp":1788998400000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp; Sci"],"published-print":{"date-parts":[[2026,9]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n \n Despite a widespread periodic vaccination with inactivated\n Pasteurella multocida biotype A<\/jats:italic>\n is usually practiced, pasteurellosis is among the most prioritized infectious diseases of small ruminant that causes huge economical loss through reduced productivity and death.\n <\/jats:p>\n <\/jats:sec>\n \n Method<\/jats:title>\n \n A cross\u2010sectional study was conducted with the objective of serotype identification and seroprevalence estimation of ovine and caprine pasteurellosis in selected districts of Afar region, Ethiopia, from December 2021 to June 2023. A total of 293 serum samples were collected using multistage sampling approach. Based on the selection of the study districts, individual animals were randomly selected for sample collection from apparently healthy sheep and goats. The samples were analyzed using the indirect haemagglutination test (IHAT) for serotyping and overall seroprevalence estimation. Descriptive statistics and Pearson's chi\u2010square (\n \u03c7<\/jats:italic>\n 2<\/jats:sup>\n ) test were employed to estimate the seroprevalence and assess the associated factors of ovine and caprine pasteurellosis in the study areas.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n In the present study, the estimated overall seroprevalence of pasteurellosis in small ruminant was found to be 97.61% (\n n<\/jats:italic>\n = 286\/293; 95% CI: 95\u2013100), of which 98.11% of the sheep (156\/159) and 97.01% (130\/134) of the goats tested positive for\n Pasteurella<\/jats:italic>\n infection. Moreover, four serotypes of\n Pasteurella<\/jats:italic>\n (A1, A2, A7 of\n Pasteurella haemolytica<\/jats:italic>\n and serotype A of\n Pasteurella multocida<\/jats:italic>\n ) were serotyped, and 89.16% of the seropositive animals had co\u2010infection with more than three serotypes. Accordingly,\n M. haemolytica serotype<\/jats:italic>\n A7 (97.27%) had the highest prevalent circulating serotypes of\n Pasteurella<\/jats:italic>\n in the study areas, followed by\n M<\/jats:italic>\n . haemolytica serotype A1 (95.22%),\n P. multocida<\/jats:italic>\n serotype A (92.83%), and\n M<\/jats:italic>\n . haemolytica serotype A2 (91.47%). There was a statistically significant difference across sex (\n p<\/jats:italic>\n = 0.014) of the study animals with the occurrence of the ovine and caprine pasteurellosis in serum samples.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n The present study revealed that ovine and caprine pasteurellosis is highly prevalent in small ruminants and circulating in the study areas. The diversity of serotypes observed here would indicate that currently available vaccines are unlikely to provide adequate protection against pasteurellosis. Therefore, developing a multivalent vaccine that protects against multiple\n Pasteurella<\/jats:italic>\n serotypes in a single dose is highly recommended.\n <\/jats:p>\n <\/jats:sec>\n \n Clinical Trial Registration<\/jats:title>\n Clinical trial registration was not required because the present study was a cross\u2010sectional observational study and did not involve any clinical intervention or experimental treatment.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/vms3.71178","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T01:11:21Z","timestamp":1789089081000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Serotyping and Seroprevalence Estimation of Pasteurellosis in Ovine and Caprine in Selected Districts of Afar Region, Ethiopia"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7026-6267","authenticated-orcid":false,"given":"Teshager","family":"Dubie","sequence":"first","affiliation":[{"name":"Department of Veterinary Medicine College of Veterinary Medicine and Animal Sciences Samara University Samara Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biniam","family":"Abera","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine College of Veterinary Medicine and Animal Sciences Samara University Samara Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7704-4170","authenticated-orcid":false,"given":"Muhammed","family":"Hamid","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine College of Veterinary Medicine and Animal Sciences Samara University Samara Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-0198-3212","authenticated-orcid":false,"given":"Tesfaw","family":"Molla","sequence":"additional","affiliation":[{"name":"Sirinka Agricultural Research Center Woldia Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6049-5840","authenticated-orcid":false,"given":"Gizachew","family":"Fentahun","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine College of Veterinary Medicine and Animal Sciences Samara University Samara Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2479-4653","authenticated-orcid":false,"given":"Fanuel Bizuayehu","family":"Yihunie","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine College of Veterinary Medicine and Animal Sciences Samara University Samara Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2048-9427","authenticated-orcid":false,"given":"Wossene","family":"Negash","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine College of Veterinary Medicine and Animal Sciences Samara University Samara Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6975-2994","authenticated-orcid":false,"given":"Sadam","family":"Mohammed","sequence":"additional","affiliation":[{"name":"Department of Pathobiology College of Veterinary Medicine and Animal Sciences University of Gondar Gondar Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bereket","family":"Desalegn","sequence":"additional","affiliation":[{"name":"Department of Pathobiology College of Veterinary Medicine and Animal Sciences University of Gondar Gondar Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,10]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2017.02.017"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11250-018-1613-8"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.21203\/rs.3.rs\u20103710096\/v1"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2019.00417"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13104-018-3606-0"},{"issue":"4","key":"e_1_2_13_7_1","first-page":"274","article-title":"Epidemiologic and Serologic Investigation of Multifactorial Respiratory Disease of Sheep in the Central Highland of Ethiopia","volume":"2","author":"Ayelet G.","year":"2004","journal-title":"International Journal of Applied Research in Veterinary 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