{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T12:54:27Z","timestamp":1791204867270,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T00:00:00Z","timestamp":1787529600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T00:00:00Z","timestamp":1787529600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp;amp; Sci"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Leiomyosarcoma (LMS), a malignant neoplasm of smooth muscle cell origin, is relatively rare in birds. This study presents the occurrence of this tumour in a 2\u2010year\u2010old male budgerigar. The bird was brought to the Ashian Veterinary Hospital with complaints of swelling in the medial area of the left leg. Clinical examination and radiological imaging confirmed the presence of soft tissue swelling in the medial region of the left leg. Empirical antibiotic and anti\u2010inflammatory therapy were used to distinguish infectious inflammation from the tumour mass. After 12 days, a clinical diagnosis of suspected neoplasm was made due to a lack of improvement and increasing mass size. Given the deterioration of the bird's general condition, euthanasia was recommended and performed. At necropsy, all viscera were biopsied for histopathological evaluation. Microscopic examinations confirmed the initial diagnosis of LMS. To confirm the diagnosis, immunohistochemical staining was performed using antibodies to alpha\u2010smooth muscle actin (\u03b1\u2010SMA), vimentin and desmin. The results of \u03b1\u2010SMA and desmin staining definitively confirmed the presence of an LMS neoplasm with metastasis to the bone and kidneys; however, vimentin staining was negative.<\/jats:p>","DOI":"10.1002\/vms3.71199","type":"journal-article","created":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T04:37:11Z","timestamp":1787632631000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Metastatic Leiomyosarcoma Involving Bone and Kidney in an Adult Budgerigar (\n                    <i>Melopsittacus undulatus<\/i>\n                    )"],"prefix":"10.1002","volume":"12","author":[{"given":"Hemad","family":"Shafiei","sequence":"first","affiliation":[{"name":"Department of Clinical Science, Faculty of Veterinary Medicine Shahid Bahonar University of Kerman  Kerman Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reza","family":"Kheirandish","sequence":"additional","affiliation":[{"name":"Department of Pathobiology, Faculty of Veterinary Medicine Shahid Bahonar University of Kerman  Kerman Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-9794-7934","authenticated-orcid":false,"given":"Hamzeh","family":"Soltani","sequence":"additional","affiliation":[{"name":"Department of Clinical Science, Faculty of Veterinary Medicine Shahid Bahonar University of Kerman  Kerman Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-5209-1379","authenticated-orcid":false,"given":"Ali","family":"Keshavarzrad","sequence":"additional","affiliation":[{"name":"Doctor of Veterinary Medicine, Faculty of Veterinary Medicine Shahid Bahonar University of Kerman Kerman Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahriar","family":"Dabiri","sequence":"additional","affiliation":[{"name":"Department of Pathology, Pathology and Stem Cell Research Center, Afzalipour Faculty of Medicine Kerman University of Medical Sciences  Kerman Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,24]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11259-026-11121-7"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1590\/0103-8478cr20180858"},{"issue":"2","key":"e_1_2_11_4_1","first-page":"89","article-title":"Pathological and Immunohistochemical Diagnosis of an Intestinal Leiomyosarcoma in a Zebra Finch","volume":"7","author":"Cardoso J. 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