{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:16:38Z","timestamp":1772118998948,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,2,9]],"date-time":"2022-02-09T00:00:00Z","timestamp":1644364800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp; Sci"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Whether abundance of glucose transporter mRNAs in the small intestine of pigs shows circadian rhythms and its regulation by clock genes was still unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>We examined whether the abundance of glucose transporters and clock genes mRNAs in the small intestine of pigs shows circadian rhythms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Twenty barrows (4 weeks old) were reared under 12 h bright and 12 h dark lighting conditions. During the 3\u2010week feeding trial, pigs were allowed free access to feed. The abundances of the mRNA of glucose transporters\n                      <jats:italic>(SGLT1<\/jats:italic>\n                      and\n                      <jats:italic>GLUT2<\/jats:italic>\n                      ) and clock genes (\n                      <jats:italic>Bmal1<\/jats:italic>\n                      ,\n                      <jats:italic>Per1<\/jats:italic>\n                      ,\n                      <jats:italic>Per2<\/jats:italic>\n                      , and\n                      <jats:italic>Cry2<\/jats:italic>\n                      ) in the intestine were measured at four time points (ZT2, ZT8, ZT14, and ZT20).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In the jejunum, the abundance of\n                      <jats:italic>SGLT1<\/jats:italic>\n                      mRNA was higher at ZT20 and ZT2 and lower at ZT8 and ZT14 (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.05). The abundances of\n                      <jats:italic>GLUT2<\/jats:italic>\n                      mRNA in the jejunum at ZTs 20 and 2 were tended to be higher than those at ZTs 8 and 14 (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.05). In the jejunum, the abundance of\n                      <jats:italic>Bmal1<\/jats:italic>\n                      mRNA was higher at ZT8 and ZT14 than at ZT20 and ZT2 (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.05). Further, the abundance of\n                      <jats:italic>Per1<\/jats:italic>\n                      mRNA at ZT2 was higher than those at the other sampling times (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.05). The abundance of\n                      <jats:italic>Per1<\/jats:italic>\n                      mRNA at ZT8 was higher than that at ZT14 (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.05), while that of\n                      <jats:italic>Per2<\/jats:italic>\n                      mRNA was higher at ZT2 than those at ZTs 20 and 14 (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>We speculate that these circadian rhythms of abundances of glucose transporter mRNAs are regulated by the clock genes expressed in the jejunum.<\/jats:p>\n                  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