{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T02:46:56Z","timestamp":1789872416258,"version":"4.0.1"},"reference-count":83,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T00:00:00Z","timestamp":1647302400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004883","name":"Shahrekord University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004883","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp;amp; Sci"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    This review covers the challenges of broiler chickens at high altitude, with the focus on growth performance and physiological response. The review also sheds light on nutritional and management interventions that help overcome the challenges raised at high altitude. Reduced concentration of atmospheric oxygen is by far the biggest challenge that remarkably affect growth performance and livability of broiler chickens reared in high altitude area. Broiler chickens have endured intensive genetic selection, which potentially predispose them to several metabolic disorders. Hypoxia is an overriding factor that may increase the incidence of metabolic disorders, mainly ascites syndrome at high altitude. Commercial broiler strains cannot fully achieve their genetic potential when raising at highland regions. Careful nutrition and management considerations are required to prevent metabolic disorders when raising broilers at high altitude. In ovo or in\u2010feed nutraceuticals such as\n                    <jats:sc>l<\/jats:sc>\n                    \u2010carnitine and guanidinoacetic acid as well as pharmaceuticals, texture of feed and the use of proper sources and levels of dietary energy and protein are important factors that need to be carefully considered for rearing broiler chickens at high altitude. Management strategies such as lighting programs have been shown to be effective to circumvent ascites prevalence. Special breeding programs may also be considered to develop strains with resistance to ascites.\n                  <\/jats:p>","DOI":"10.1002\/vms3.784","type":"journal-article","created":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T13:54:12Z","timestamp":1647352452000},"page":"1519-1527","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Managing broiler production challenges at high altitude"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0324-9074","authenticated-orcid":false,"given":"Fariborz","family":"Khajali","sequence":"first","affiliation":[{"name":"Department of Animal Science Faculty of Agriculture Shahrekord University  Shahrekord Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,3,15]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anifeedsci.2020.114755"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.3382\/ps.0740833"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.3382\/ps\/pew193"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.3382\/ps\/pex302"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aninu.2019.04.004"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2014.10.043"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/vms3.556"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.2141\/jpsa.0170044"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/japr\/16.1.138"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.3382\/ps.0730801"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.3382\/japr.2008-00095"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/japr\/1.1.1"},{"key":"e_1_2_14_14_1","volume-title":"Ross Technical Note","author":"Aviagens","year":"2009"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.3382\/ps.0730810"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/ps\/79.8.1101"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/00071668.2012.727082"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/ps\/82.10.1550"},{"key":"e_1_2_14_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/ps\/76.11.1506"},{"key":"e_1_2_14_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/japr\/11.2.164"},{"key":"e_1_2_14_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/ps\/83.4.526"},{"key":"e_1_2_14_22_1","doi-asserted-by":"publisher","DOI":"10.5713\/ajas.1995.159"},{"key":"e_1_2_14_23_1","doi-asserted-by":"publisher","DOI":"10.1079\/WPS20000025"},{"key":"e_1_2_14_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpn.13020"},{"key":"e_1_2_14_25_1","first-page":"139","article-title":"Influence of dietary aspirin on growth performance, antioxidant status, and mortality due to ascites in broiler chickens","volume":"4","author":"Fathi M.","year":"2016","journal-title":"Poultry Science Journal"},{"key":"e_1_2_14_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00484-020-02037-1"},{"key":"e_1_2_14_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/ps\/83.9.1587"},{"key":"e_1_2_14_28_1","doi-asserted-by":"publisher","DOI":"10.5194\/aab-60-315-2017"},{"key":"e_1_2_14_29_1","doi-asserted-by":"publisher","DOI":"10.1080\/03079459708419191"},{"key":"e_1_2_14_30_1","doi-asserted-by":"publisher","DOI":"10.1080\/03079450120044173"},{"key":"e_1_2_14_31_1","first-page":"57","article-title":"Effect of intermittent lighting schedules at the young age of broiler chickens on the incidence of ascites and metabolic parameters","volume":"69","author":"Hassanzadeh M.","year":"2005","journal-title":"Archiv Fur Geflugelkunde"},{"key":"e_1_2_14_32_1","unstructured":"Hubbard Technical Report(2005).Managing broilers in the high altitudes of the Andes mountains.Technical Bulletin V\u201003\/2005."},{"key":"e_1_2_14_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anifeedsci.2009.12.009"},{"key":"e_1_2_14_34_1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2019.00082"},{"key":"e_1_2_14_35_1","first-page":"214","article-title":"The effect of dietary sodium on right ventricular failure\u2010induced ascites, gain and fat deposition in meat\u2010type chickens","volume":"56","author":"Julian R. 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