{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,28]],"date-time":"2025-06-28T20:10:02Z","timestamp":1751141402402,"version":"3.41.0"},"reference-count":40,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,12,14]],"date-time":"2017-12-14T00:00:00Z","timestamp":1513209600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Medicine &amp; Sci"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 21\u2010year\u2010old American Saddlebred mare died with a history of weight loss and breathing difficulties of 1\u00a0month duration. Post\u2010mortem examination revealed a copious pleural effusion with multifocal to coalescing numerous white to grey nodular masses on the serosal surface of the pericardium, lungs and thoracic cavity. In addition, the left thyroid gland was markedly enlarged. A thoracic mesothelioma and C\u2010cell adenoma with amyloid deposits of the left thyroid gland were diagnosed by histopathology and confirmed by immunohistochemistry employing antibodies against cytokeratin (<jats:styled-content style=\"fixed-case\">CK<\/jats:styled-content>), vimentin and calcitonin. Amyloid deposits in the thyroid tumour were confirmed by Congo red staining with apple\u2010green birefringence under polarized light. Mesothelioma remains an uncommon neoplasm encountered in aged horses. Discussion includes the diagnostic challenge of differentiating carcinomatosis from mesothelioma by histology and differentiating reactive and neoplastic mesothelial cells by cytology.<\/jats:p>","DOI":"10.1002\/vms3.87","type":"journal-article","created":{"date-parts":[[2017,12,14]],"date-time":"2017-12-14T05:29:55Z","timestamp":1513229395000},"page":"63-70","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Concurrent thoracic mesothelioma and thyroid C\u2010cell adenoma with amyloid deposition in an aged horse"],"prefix":"10.1002","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1007-9360","authenticated-orcid":false,"given":"Jessica S.","family":"Fortin","sequence":"first","affiliation":[{"name":"Veterinary Medical Diagnostic Laboratory University of Missouri Columbia Missouri USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela B.","family":"Royal","sequence":"additional","affiliation":[{"name":"Veterinary Medical Diagnostic Laboratory University of Missouri Columbia Missouri USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiichi","family":"Kuroki","sequence":"additional","affiliation":[{"name":"Veterinary Medical Diagnostic Laboratory University of Missouri Columbia Missouri USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,12,14]]},"reference":[{"key":"e_1_2_11_2_1","first-page":"77","article-title":"The Amyloid in solid carcinoma of the thyroid gland. staining characteristics, tissue culture, and electron microscopic observations","volume":"13","author":"Albores\u2010Saavedra J.","year":"1964","journal-title":"Laboratory Investigation"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cveq.2010.12.002"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2003.223.93"},{"key":"e_1_2_11_5_1","first-page":"377","article-title":"Animal model of human disease. 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