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Recently, there have been a series of consultations regarding the fact that night barking, which is an abnormal behaviour, remarkably interferes with the owner's sleep and adversely affects the owner's quality of life. However, there has been no effective solution to this problem. In this study, three aged pet dogs diagnosed with dementia were administered an equine placental extract (eqPE) as pet supplement, which has been shown in laboratory models to improve cognitive function. Consequently, night barking ceased 1\u00a0week after the administration of eqPE in case 2 and it was observed to decrease in the other two dogs. Furthermore, night barking disappeared 2 and 3\u00a0weeks after the administration of eqPE in cases 1 and 3, respectively. No recurrence or exacerbation of night barking was observed in the three cases treated with the eqPE, and no adverse events were observed. These results suggest that eqPE may be useful for improving night barking in pet dogs with dementia, and it is expected to be a new treatment method.<\/jats:p>","DOI":"10.1002\/vms3.893","type":"journal-article","created":{"date-parts":[[2022,8,3]],"date-time":"2022-08-03T13:53:51Z","timestamp":1659534831000},"page":"1887-1892","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Equine placental extract supplement as a night barking remedy in dogs with cognitive dysfunction syndrome"],"prefix":"10.1002","volume":"8","author":[{"given":"Tatsuya","family":"Amano","sequence":"first","affiliation":[{"name":"Amano Animal Hospital  Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Ikeda","sequence":"additional","affiliation":[{"name":"Momo Animal Hospital  Kobe Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makiko","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Rui Animal Hospital  Tokoname Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuhisa","family":"Kakehi","sequence":"additional","affiliation":[{"name":"Domestic Sales Department Japan Bio Products Co., Ltd.  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