{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T23:30:22Z","timestamp":1792625422112,"version":"4.5.0"},"reference-count":151,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,5,19]],"date-time":"2016-05-19T00:00:00Z","timestamp":1463616000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01GM88041"],"award-info":[{"award-number":["R01GM88041"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R03AR065760"],"award-info":[{"award-number":["R03AR065760"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R21AR068536"],"award-info":[{"award-number":["R21AR068536"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["T32 NS077984"],"award-info":[{"award-number":["T32 NS077984"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["WIREs Developmental Biology"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:p>\n                    Skeletal muscle fibers are classified into fiber types, in particular, slow twitch versus fast twitch. Muscle fiber types are generally defined by the particular myosin heavy chain isoforms that they express, but many other components contribute to a fiber's physiological characteristics. Skeletal muscle fiber type can have a profound impact on muscle diseases, including certain muscular dystrophies and sarcopenia, the aging\u2010induced loss of muscle mass and strength. These findings suggest that some muscle diseases may be treated by shifting fiber type characteristics either from slow to fast, or fast to slow phenotypes, depending on the disease. Recent studies have begun to address which components of muscle fiber types mediate their susceptibility or resistance to muscle disease. However, for many diseases it remains largely unclear why certain fiber types are affected. A substantial body of work has revealed molecular pathways that regulate muscle fiber type plasticity and early developmental muscle fiber identity. For instance, recent studies have revealed many factors that regulate muscle fiber type through modulating the activity of the muscle regulatory transcription factor\n                    <jats:styled-content style=\"fixed-case\">MYOD1<\/jats:styled-content>\n                    . Future studies of muscle fiber type development in animal models will continue to enhance our understanding of factors and pathways that may provide therapeutic targets to treat muscle diseases.\n                    <jats:italic>WIREs Dev Biol<\/jats:italic>\n                    2016, 5:518\u2013534. doi: 10.1002\/wdev.230\n                  <\/jats:p>\n                  <jats:p>\n                    This article is categorized under:\n                    <jats:list list-type=\"explicit-label\">\n                      <jats:list-item>\n                        <jats:p>Gene Expression and Transcriptional Hierarchies &gt; Regulatory Mechanisms<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>Vertebrate Organogenesis &gt; Musculoskeletal and Vascular<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>Birth Defects &gt; Organ Anomalies<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:p>","DOI":"10.1002\/wdev.230","type":"journal-article","created":{"date-parts":[[2016,5,21]],"date-time":"2016-05-21T17:15:26Z","timestamp":1463850926000},"page":"518-534","source":"Crossref","is-referenced-by-count":439,"title":["Skeletal muscle fiber type: using insights from muscle developmental biology to dissect targets for susceptibility and resistance to muscle disease"],"prefix":"10.1002","volume":"5","author":[{"given":"Jared","family":"Talbot","sequence":"first","affiliation":[{"name":"Department of Molecular Genetics The Ohio State University  Columbus OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Maves","sequence":"additional","affiliation":[{"name":"Center for Developmental Biology and Regenerative Medicine Seattle Children's Research Institute  Seattle, WA USA"},{"name":"Department of Pediatrics University of Washington  Seattle WA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,5,19]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00031.2010"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.biochem.75.103004.142622"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0029(20000915)50:6<500::AID-JEMT7>3.0.CO;2-7"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-004-0448-4"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4886(69)90077-6"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-1281(80)80024-9"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1953.sp004948"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1969.sp008771"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13578-015-0054-6"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/embor.2008.73"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2836(88)90145-3"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms9071259"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-13-181"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms16059635"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00438-015-1138-z"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2199-14-7"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.2527\/jas.2012-5371"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(73)90023-3"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(88)90463-1"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/0960-8966(91)90003-B"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1999.0213"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e318282513b"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.200600056"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000065898.61358.09"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21122"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4598(200004)23:4<529::AID-MUS11>3.0.CO;2-Y"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.spen.2011.10.008"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2013.250"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2010.12.011"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/humu.22553"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2014.12.098"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.4161\/auto.2984"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddn292"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.1995.268.3.E453"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00416.2001"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.29.04.06.dc05-1854"},{"key":"e_1_2_7_38_1","first-page":"37","article-title":"Muscle fiber composition in patients with traumatic cord lesion","volume":"8","author":"Grimby G","year":"1976","journal-title":"Scand J Rehabil Med"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-201X.2005.01457.x"},{"key":"e_1_2_7_40_1","first-page":"11","article-title":"Human aging, muscle mass, and fiber type composition","volume":"50","author":"Lexell J","year":"1995","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2013.02.012"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/71.5.1033"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70271-6"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.1992.0058"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00121296"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1993.265.3.C834"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2474-9-1"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1186\/2044-5040-4-12"},{"key":"e_1_2_7_49_1","first-page":"154","article-title":"Clinical aspects, molecular pathomechanisms and management of myotonic dystrophies","volume":"32","author":"Meola G","year":"2013","journal-title":"Acta Myol"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1002\/humu.22554"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2014.02.036"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-012-1024-2"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2014.00177"},{"key":"e_1_2_7_54_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10545-012-9541-7"},{"key":"e_1_2_7_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2004.09.017"},{"key":"e_1_2_7_56_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0015239"},{"key":"e_1_2_7_57_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21391"},{"key":"e_1_2_7_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2013.05.016"},{"key":"e_1_2_7_59_1","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.50.6.1324"},{"key":"e_1_2_7_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(90)90933-V"},{"key":"e_1_2_7_61_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2012-3876"},{"key":"e_1_2_7_62_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1180"},{"key":"e_1_2_7_63_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1032913100"},{"key":"e_1_2_7_64_1","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.50.4.817"},{"key":"e_1_2_7_65_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.sc.3100364"},{"key":"e_1_2_7_66_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00560.2007"},{"key":"e_1_2_7_67_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.10534"},{"key":"e_1_2_7_68_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.1990.tb08975.x"},{"key":"e_1_2_7_69_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00129.2005"},{"key":"e_1_2_7_70_1","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.52.12.2874"},{"key":"e_1_2_7_71_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.2006.01620.x"},{"key":"e_1_2_7_72_1","first-page":"207","article-title":"Transcriptional co\u2010activator PGC\u20101 alpha drives the formation of slow\u2010twitch muscle fibres","volume":"188","author":"Lin J","year":"2002","journal-title":"Nature"},{"key":"e_1_2_7_73_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0607795103"},{"key":"e_1_2_7_74_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00790.2012"},{"key":"e_1_2_7_75_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2007.078980"},{"key":"e_1_2_7_76_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00778.2013"},{"key":"e_1_2_7_77_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.13-238071"},{"key":"e_1_2_7_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2014.01.006"},{"key":"e_1_2_7_79_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1525107"},{"key":"e_1_2_7_80_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.2001.281.4.C1300"},{"key":"e_1_2_7_81_1","first-page":"209","article-title":"Utrophin upregulation in Duchenne muscular dystrophy","volume":"24","author":"Hirst RC","year":"2005","journal-title":"Acta Myol"},{"key":"e_1_2_7_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2006.01.002"},{"key":"e_1_2_7_83_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddv154"},{"key":"e_1_2_7_84_1","doi-asserted-by":"publisher","DOI":"10.1186\/2044-5040-4-2"},{"key":"e_1_2_7_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80532-2"},{"key":"e_1_2_7_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80533-4"},{"key":"e_1_2_7_87_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddu535"},{"key":"e_1_2_7_88_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddr265"},{"key":"e_1_2_7_89_1","doi-asserted-by":"publisher","DOI":"10.1186\/2044-5040-2-16"},{"key":"e_1_2_7_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2012.04.004"},{"key":"e_1_2_7_91_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00221.2012"},{"key":"e_1_2_7_92_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.1993.tb09493.x"},{"key":"e_1_2_7_93_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb3107"},{"key":"e_1_2_7_94_1","doi-asserted-by":"publisher","DOI":"10.1111\/acel.12153"},{"key":"e_1_2_7_95_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0911570106"},{"key":"e_1_2_7_96_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/dds049"},{"key":"e_1_2_7_97_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1101-1014"},{"key":"e_1_2_7_98_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1101-1009"},{"key":"e_1_2_7_99_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(04)00400-3"},{"key":"e_1_2_7_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2007.11.003"},{"key":"e_1_2_7_101_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-185X.2010.00161.x"},{"key":"e_1_2_7_102_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1960.sp006395"},{"key":"e_1_2_7_103_1","doi-asserted-by":"publisher","DOI":"10.1002\/cphy.c130009"},{"key":"e_1_2_7_104_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1972.33.3.312"},{"key":"e_1_2_7_105_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1976.40.2.149"},{"key":"e_1_2_7_106_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.1978.tb06272.x"},{"key":"e_1_2_7_107_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.1993.tb09618.x"},{"key":"e_1_2_7_108_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.1994.tb09730.x"},{"key":"e_1_2_7_109_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00830.2002"},{"key":"e_1_2_7_110_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0838.2011.01305.x"},{"key":"e_1_2_7_111_1","doi-asserted-by":"publisher","DOI":"10.1519\/JSC.0b013e318234eb6f"},{"key":"e_1_2_7_112_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.12.16.2499"},{"key":"e_1_2_7_113_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0812911106"},{"key":"e_1_2_7_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2014.08.035"},{"key":"e_1_2_7_115_1","doi-asserted-by":"publisher","DOI":"10.2337\/db07-0255"},{"key":"e_1_2_7_116_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0705070104"},{"key":"e_1_2_7_117_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00481.2009"},{"key":"e_1_2_7_118_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-014-1604-5"},{"key":"e_1_2_7_119_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mod.2013.06.001"},{"key":"e_1_2_7_120_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.187385.112"},{"key":"e_1_2_7_121_1","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/mss125"},{"key":"e_1_2_7_122_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.28755"},{"key":"e_1_2_7_123_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1004386"},{"key":"e_1_2_7_124_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2009.11.031"},{"key":"e_1_2_7_125_1","doi-asserted-by":"publisher","DOI":"10.1038\/gt.2014.13"},{"key":"e_1_2_7_126_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2009.10.013"},{"key":"e_1_2_7_127_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.143677"},{"key":"e_1_2_7_128_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.24.14.6253-6267.2004"},{"key":"e_1_2_7_129_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.01874"},{"key":"e_1_2_7_130_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2005.07.006"},{"key":"e_1_2_7_131_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0925-4773(96)00631-4"},{"key":"e_1_2_7_132_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.2001.280.2.C408"},{"key":"e_1_2_7_133_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2007.141457"},{"key":"e_1_2_7_134_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21637"},{"key":"e_1_2_7_135_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.003905"},{"key":"e_1_2_7_136_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1281105"},{"key":"e_1_2_7_137_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7600958"},{"key":"e_1_2_7_138_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2010.02.014"},{"key":"e_1_2_7_139_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2012.05.046"},{"key":"e_1_2_7_140_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gde.2013.05.002"},{"key":"e_1_2_7_141_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1097-2765(04)00260-6"},{"key":"e_1_2_7_142_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms4793"},{"key":"e_1_2_7_143_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2015.10.008"},{"key":"e_1_2_7_144_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.20916"},{"key":"e_1_2_7_145_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M109.022749"},{"key":"e_1_2_7_146_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.004739"},{"key":"e_1_2_7_147_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkq585"},{"key":"e_1_2_7_148_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0067762"},{"key":"e_1_2_7_149_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1107413108"},{"key":"e_1_2_7_150_1","doi-asserted-by":"publisher","DOI":"10.1242\/bio.20133921"},{"key":"e_1_2_7_151_1","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.010082"},{"key":"e_1_2_7_152_1","doi-asserted-by":"publisher","DOI":"10.1517\/17460441.2014.927435"}],"container-title":["WIREs Developmental Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fwdev.230","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fwdev.230","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/wdev.230","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/wdev.230","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/wires.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/wdev.230","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,27]],"date-time":"2023-08-27T23:09:17Z","timestamp":1693177757000},"score":1,"resource":{"primary":{"URL":"https:\/\/wires.onlinelibrary.wiley.com\/doi\/10.1002\/wdev.230"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5,19]]},"references-count":151,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["10.1002\/wdev.230"],"URL":"https:\/\/doi.org\/10.1002\/wdev.230","archive":["Portico"],"relation":{},"ISSN":["1759-7684","1759-7692"],"issn-type":[{"value":"1759-7684","type":"print"},{"value":"1759-7692","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,5,19]]}}}