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We investigated surface water, groundwater, sediment, and borehole\u2010core samples from the Jiulong River Estuary and Dongxixi River Estuary, China. Antibiotic contamination was relatively more pronounced in the Jiulong River Estuary, whereas microplastic abundance, particularly in sediments, was higher in the Dongxixi River Estuary. In borehole XTZ02, both contaminants showed shallow subsurface enrichment within their overlapping depth range; microplastics &gt;\u2009300\u2009\u03bcm occurred only in shallow intervals, consistent with size\u2010selective subsurface redistribution. Total antibiotic concentrations were not significantly correlated with total microplastic abundance, and RDA identified no statistically significant overall environmental control. These findings highlight matrix\u2010dependent contaminant behavior across the estuary\u2013vadose zone\u2013groundwater\u2013sediment continuum.<\/jats:p>","DOI":"10.1002\/wer.70574","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:51:40Z","timestamp":1790643100000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Co\u2010Occurrence and Vertical Distribution of Antibiotics and Microplastics across Multiple Environmental Media in Typical Subtropical Estuaries"],"prefix":"10.1002","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-5380-8678","authenticated-orcid":false,"given":"Xinyu","family":"Yang","sequence":"first","affiliation":[{"name":"School of Environmental and Municipal Engineering Xi'an University of Architecture and Technology  Xi'an China"},{"name":"Fujian Provincial Key Laboratory of Water Cycling and Eco\u2010Geological Processes, Institute of 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