{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T01:04:11Z","timestamp":1790643851453,"version":"4.1.0"},"reference-count":38,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T00:00:00Z","timestamp":1790467200000},"content-version":"vor","delay-in-days":26,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Water Environment Research"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Pharmaceutical residues in aquatic environments require reusable sorbents capable of removing structurally diverse contaminants under competitive conditions. Here, a hydrophobic natural deep eutectic solvent\u2010coated silica composite (DES\u2010SOT) was prepared by functionalizing silica gel with\n                    <jats:italic>n<\/jats:italic>\n                    \u2010octyltriethoxysilane followed by immobilization of a thymol:oleic acid deep eutectic solvent. Characterization confirmed formation of a DES\u2010rich organic interfacial layer. DES\u2010SOT showed higher adsorption capacities than unmodified silica and Si\u2010OTES for diclofenac, ibuprofen, mefenamic acid, and tolfenamic acid, with equilibrium reached within 20\u2009min at pH\u20096. Kinetic and isotherm analyses described heterogeneous adsorption behavior, while reusability, desorption, and molecular dynamics results were consistent with hydrophobic partitioning and weak noncovalent interactions. Molecular dynamics simulations supported analyte\u2010dependent association with the DES\u2010rich interface, consistent with experimental adsorption trends. DES\u2010SOT maintained adsorption performance in groundwater and lake water and remained reusable over five adsorption\u2013desorption cycles. This study demonstrates a simple DES\u2010based adsorption interface for pharmaceutical removal from water.\n                  <\/jats:p>","DOI":"10.1002\/wer.70609","type":"journal-article","created":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T05:14:16Z","timestamp":1790572456000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hydrophobic Deep Eutectic Solvent\u2010Coated Silica Gel for NSAID Adsorption From Water: Performance and Interfacial Mechanism"],"prefix":"10.1002","volume":"98","author":[{"given":"Siti Adilah","family":"Sabarudin","sequence":"first","affiliation":[{"name":"Department of Chemistry, Faculty of Science Universiti Malaya  Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7176-441X","authenticated-orcid":false,"given":"Nobuyuki","family":"Matubayasi","sequence":"additional","affiliation":[{"name":"Division of Chemical Engineering, Graduate School of Engineering Science The University of Osaka  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vannajan Saghiran","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Science Universiti Malaya  Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0304-0617","authenticated-orcid":false,"given":"Muggundha","family":"Raoov","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Science Universiti Malaya  Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1402-6175","authenticated-orcid":false,"given":"Kheng Soo","family":"Tay","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Science Universiti Malaya  Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,27]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seppur.2021.118585"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2021.128472"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.20517\/wecn.2023.06"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2009.02.072"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2013.04.003"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.2136\/sssaj1980.03615995004400020013x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.iecr.4c01895"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.2c07684"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1021\/cm500365c"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/ph17010124"},{"key":"e_1_2_8_12_1","volume-title":"Water Purification\u2014Present and Future","author":"Garc\u00eda M. 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